Results 61 to 70 of about 1,513,668 (313)
Mixed-effect linear regression candidate models.
, 2019 Mixed-effect linear regression candidate models.
Jason Parker (2050768) +9 more
core +1 more source
Unraveling the genetic potential of Indian rice germplasm for reproductive stage drought tolerance
Frontiers in Plant ScienceClimate change poses a serious threat to future food security on a global scale. Drought is the most challenging abiotic stress, limiting rice production in rainfed rice ecosystems. Therefore, an experiment was designed under three distinct environments,
Santhiya Subramanian +9 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Revista Brasileira de Zootecnia, 2007 Quatro diferentes tipos de população foram simulados com o objetivo de verificar a influência de genes de efeito principal e do tamanho da população na estimação de componentes de variância sob seleção.
Giselle Mariano Lessa de Assis +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Mixed Methods for Mixed Models
, 2014 This work bridges the frequentist and Bayesian approaches to mixed models by borrowing the best features from both camps: point estimation procedures are combined with priors to obtain accurate, fast inference while posterior simulation techniques are developed that approximate the likelihood with great precision for the purposes of assessing ...
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Smooth-car mixed models for spatial count data [PDF]
, 2008 Penalized splines (P-splines) and individual random effects are used for the analysis of spatial count data. P-splines are represented as mixed models to give a unified approach to the model estimation procedure.
Durbán, María, Lee, Dae-Jin
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Pesquisa Agropecuária Brasileira, 2009 Os objetivos deste trabalho foram determinar a interação genótipo x ambiente e a estabilidade e adaptabilidade da produção de borracha em progênies de seringueira (Hevea brasiliensis (Willd. ex A. Juss.) Müll. Arg.), bem como estimar o ganho genético com
Cecília Khusala Verardi +3 more
doaj +1 more source