Results 11 to 20 of about 3,858,904 (290)

Likelihood Function through the Delta Approximation in Mixed SDE Models

open access: yesMathematics, 2022
Stochastic differential equations (SDE) appropriately describe a variety of phenomena occurring in random environments, such as the growth dynamics of individual animals.
Nelson T. Jamba   +3 more
doaj   +1 more source

Multiple testing correction in linear mixed models. [PDF]

open access: yes, 2016
BackgroundMultiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes ...
Eskin, Eleazar   +3 more
core   +2 more sources

Mixed Markov models [PDF]

open access: yesProceedings of the National Academy of Sciences, 2003
Markov random fields can encode complex probabilistic relationships involving multiple variables and admit efficient procedures for probabilistic inference. However, from a knowledge engineering point of view, these models suffer from a serious limitation.
openaire   +3 more sources

Taming Human Genetic Variability: Transcriptomic Meta-Analysis Guides the Experimental Design and Interpretation of iPSC-Based Disease Modeling

open access: yesStem Cell Reports, 2017
Both the promises and pitfalls of the cell reprogramming research platform rest on human genetic variation, making the measurement of its impact one of the most urgent issues in the field.
Pierre-Luc Germain, Giuseppe Testa
doaj   +1 more source

Age and diet shape the genetic architecture of body weight in diversity outbred mice

open access: yeseLife, 2022
Understanding how genetic variation shapes a complex trait relies on accurately quantifying both the additive genetic and genotype–environment interaction effects in an age-dependent manner. We used a linear mixed model to quantify diet-dependent genetic
Kevin M Wright   +6 more
doaj   +1 more source

The Parisi formula for mixed $p$-spin models [PDF]

open access: yes, 2014
The Parisi formula for the free energy in the Sherrington-Kirkpatrick and mixed $p$-spin models for even $p\geq2$ was proved in the seminal work of Michel Talagrand [Ann. of Math. (2) 163 (2006) 221-263].
Panchenko, Dmitry
core   +3 more sources

Flexible semiparametric mixed models [PDF]

open access: yes, 2005
In linear mixed models the influence of covariates is restricted to a strictly parametric form. With the rise of semi- and nonparametric regression also the mixed model has been expanded to allow for additive predictors.
Reithinger, Florian, Tutz, Gerhard
core   +2 more sources

Stability and adaptability of curled green-leaf lettuce lines using the REML/Blup mixed model [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2018
: The objective of this work was to estimate the stability and genotypic adaptability of advanced lines and cultivars of curled green-leaf lettuce (Lactuca sativa), in different growing environments and seasons, using the REML/Blup mixed model.
Willame dos Santos Candido   +6 more
doaj   +1 more source

R-environment package for regression analysis [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2018
: The objective of this work was to develop a package in the R environment for automating and facilitating the regression analysis. Named easyreg, the package offers five functions.
Emmanuel Arnhold
doaj   +1 more source

Generalized fiducial inference for normal linear mixed models [PDF]

open access: yes, 2012
While linear mixed modeling methods are foundational concepts introduced in any statistical education, adequate general methods for interval estimation involving models with more than a few variance components are lacking, especially in the unbalanced ...
Cisewski, Jessi, Hannig, Jan
core   +4 more sources

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