Results 121 to 130 of about 780,588 (296)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Impact of a synthetic zeolite mixed with soils of different pedological characteristics on soil physical quality indices

Geoderma
The addition of natural or synthetic zeolites induces changes in a soil’s chemical, physical, and biological characteristics. Zeolites possess intricate internal frameworks that allow them to modify soil structure and texture, thereby impacting soil ...
Antonio Satriani, Claudia Belviso, Stella Lovelli, Simone di Prima, Antonio Coppola, Shawkat B.M. Hassan, Anna Rita Rivelli, Alessandro Comegna   +7 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Customer Relationship Management and Service Quality: a qualitative study

, 2015
This study examined customer relationship management effectiveness and Service quality on international customers in a single University in the UK higher education sector.
Wali, Andy Fred, Nwokah, N.Gladson, Wright, Len Tiu, Reynolds, Paul Lewis   +3 more
core  

Investigating classroom quality in a Head Start context: a mixed methods approach

Hustedt, Jason T.Quality in early care and education (ECE) has been widely studied across several decades. There is not one standard definition of quality across ECE contexts.
Kelly, Cara L.
core   +1 more source

Quality Characteristics of Mixed Makgeolli with Barley and Wheat

The Korean Journal of Food And Nutrition, 2016
Dong-Sun Shin, Ye-Ji Choi, Seok-Tae Jeong, Eun-Yeong Sim, Seuk Ki Lee, Hyun-Joo Kim, Koan Sik Woo, Si-Ju Kim, Sea-Kwan Oh, Hye-Young Park   +9 more
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Volatile Compounds and Quality Characteristics of Fresh-Cut Apples and Mixed Fruits Coated with Ascorbic Acid during Cold Storage

Fresh-cut apples are commonly known as minimally processed agricultural products because of their convenience and ease of consumption. However, during storage, the quality of the apple rapidly changes after cutting due to enzymatic and non-enzymatic ...
Jae-Hwan Ahn, Jong-Hoon Kim, Andri Jaya Laksana, Ji-Young Kim   +3 more
core   +1 more source

Replacing alfalfa-based total mixed ration with Moringa leaves for improving carcass and meat quality characteristics in lambs

Heliyon
The expected increase in the population will put more pressure on resources, which means there will be a greater demand for food and the need for different ingredients to feed animals.
Khalid A. Abdoun, Gamaleldin M. Suliman, Ahmed A. Alsagan, Osman A. Altahir, Mohammed Y. Alsaiady, Elfadil E. Babiker, Mohammed A. Al-Badwi, Faisal A. Alshamiry, Ahmed A. Al-Haidary   +8 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source