Results 61 to 70 of about 143,948 (315)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

HiFinger: One-Handed Text Entry Technique for Virtual Environments Based on Touches between Fingers

open access: yesSensors, 2019
We present a text entry technique called HiFinger, which is an eyes-free, one-handed wearable text entry technique for immersive virtual environments by thumb-to-fingers touch.
Haiyan Jiang   +3 more
doaj   +1 more source

Maskwarp: visuo-haptic illusions in mixed reality using real-time video inpainting

open access: yes, 2023
We present MaskWarp, a novel approach to enable haptic retargeting and other visuo-haptic illusions in video see-through (VST) mixed reality (MR). Virtual reality provides a unique ability to shift where users perceive their virtual hands.
Matthews, B.J.   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Mixed Reality: A Survey

open access: yes, 2009
This chapter presents an overview of the Mixed Reality (MR) paradigm, which proposes to overlay our real-world environment with digital, computer-generated objects.
Costanza, Enrico   +5 more
core   +1 more source

Spacedesign: A mixed reality workspace for aesthetic industrial design

open access: yes, 2022
S.86-94Spacedesign is an innovative Mixed Reality (MR) application addressed to aesthetic design of free form curves and surfaces. It is a unique and comprehensive approach which uses task-specific configurations to support the design workflow from ...
Monno, G.   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Nonmechanical varifocal metalens using nematic liquid crystal

open access: yesNanophotonics, 2023
Metalenses exhibit a substantial potential in replacing traditional optical component as they present a methodology for miniaturization. Lenses with tunable focal lengths can play a key role in various fields with applications in imaging, displays, and ...
Zhu Shuangqi   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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