Results 81 to 90 of about 3,509,796 (312)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Solution Processed Trilayer Structure for High-Performance Perovskite Photodetector

Nanoscale Research Letters, 2018
Due to their outstanding performance, low cost, ease of fabrication, diverse photonic, and optoelectronic applications, metal halides perovskite have attracted extensive interest in photodetector applications.
Abbas Ahmad Khan, Zhinong Yu, Ubaid Khan, Lin Dong   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Ultrasensitive metasurface sensor based on quasi-bound states in the continuum

Nanophotonics
The quasi-bound state in the continuum (quasi-BIC) of dielectric metasurface provides a crucial platform for sensing, because its almost infinite Q-factor can greatly enhance the interactions between light waves and the analytes.
Li Ning, Chen He, Zhao Yunxia, Wang Yongtian, Su Zhaoxian, Liu Yin, Huang Lingling   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Multichannel Fully Convolutional Network for Coronary Artery Segmentation in X-Ray Angiograms

IEEE Access, 2018
Accurate segmentation of coronary arteries in X-ray angiograms is an important step for the quantitative study of coronary artery disease. However, accurate segmentation is a challenging task because coronary arteries are thin tubular structures with ...
Jingfan Fan, Jian Yang, Yachen Wang, Siyuan Yang, Danni Ai, Yong Huang, Hong Song, Aimin Hao, Yongtian Wang   +8 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

PAR-Net: An Enhanced Dual-Stream CNN–ESN Architecture for Human Physical Activity Recognition

Sensors
Physical exercise affects many facets of life, including mental health, social interaction, physical fitness, and illness prevention, among many others.
Imran Ullah Khan, Jong Weon Lee
doaj   +1 more source