Results 121 to 130 of about 586,058 (292)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

Cooperative Merging in Mixed Traffic Based on Strategic Influence of Connected Automated Vehicles on Human‐Driven Vehicle Behavior

open access: yesAdvanced Intelligent Systems
Cooperative on‐ramp merging control for connected and automated vehicles (CAVs) can significantly enhance traffic flow and fuel efficiency at highway merging points. However, in mixed traffic scenarios where CAVs coexist with human‐driven vehicles (HDVs),
Kyunghwan Choi   +2 more
doaj   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

open access: yesAdvanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer   +10 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

Control strategies for multiple transportation modes in urban road networks

open access: yesJournal of Highway and Transportation Research and Development
The study leverages the three-dimensional Macroscopic Fundamental Diagram (3D MFD) model for urban road networks and constructs a refined 3D MFD model utilizing the actual movement trajectory data of diverse vehicles within the experimental region.
Zhonghe He, Jianming Wang, Jiaxin Wang
doaj   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini   +2 more
wiley   +1 more source

Uplink Power Control Optimization for XR and eMBB Co-Existence in 5G-Advanced Networks

open access: yesIEEE Access
This paper presents an analysis of fifth-generation (5G)-Advanced uplink system-level performance with the coexistence of extended reality (XR) and enhanced mobile broadband (eMBB) traffic.
Pouria Paymard   +6 more
doaj   +1 more source

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