Results 81 to 90 of about 3,746,167 (305)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
OncoLog: A Report to Physicians
, 1983 Quarterly newsletter from the University of Texas System Cancer Center, M.D.
Eisen, Leslie L. +1 more
core
Mixed Adenoneuroendocrine Tumor of the Perianal Skin
World Journal of Colorectal Surgery, 2019 Mixed adenoneuroendocrine carcinoma (MANEC) of the intestinal tract, is relatively rare and with a poor prognosis. The majority of literature to date has documented the rare occurrence of this tumor within the colon or rectum, but not within the anal ...
Daniel J. Mullins, Robert T. Lewis
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Engaging the Immune Response to Normalize the Tumor Microenvironment [PDF]
, 2013 Solid tumors exist as heterogeneous populations comprised not only of malignant cells, but various other cell types, including cells that make up the vasculature, that can strongly influence tumorgenicity.
Sabins, Nina, Storkus, Walter
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Newsletter: A Report to the Physicians of Texas
, 1982 Quarterly newsletter from the University of Texas System Cancer Center, M.D. Anderson Hospital and Tumor Institute discussing cancer care and research to inform physicians of recent developments in the ...
Eisen, Leslie L. +1 more
core +1 more source
Odontogenic carcinosarcoma of the mandible: A case report
Clinical Case ReportsKey Clinical Message Odontogenic carcinosarcoma, a rare and challenging diagnosis, was identified in a 60‐year‐old male through histopathology, revealing a biphasic neoplasm with malignant epithelial and mesenchymal components.
Pouyan Aminishakib +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Journal of Medical Case Reports, 2011 Introduction Extragenital malignant mixed Müllerian tumor is an extremely rare presentation of malignant mixed Müllerian tumor, especially when combined with a synchronous ovarian cancer.
Chan Te-Fu +4 more
doaj +1 more source