Results 71 to 80 of about 3,746,167 (305)

Mathematical modeling of tumor growth and treatment [PDF]

, 2014
Using mathematical models to simulate dynamic biological processes has a long history. Over the past couple of decades or so, quantitative approaches have also made their way into cancer research.
Chaplain, Mark A. J., Enderling, Heiko
core   +1 more source

Diagnosis and treatment of mixed salivary gland tumor previously diagnosed as cutaneous chondroid syringoma proximal to the oral commissure: A case report

Clinical Case Reports
Key Clinical Message Subcutaneous tumors of the head and neck resembling cutaneous mixed tumors may be misdiagnosed pleomorphic adenomas of salivary gland origin.
Haeseong Lee, Navid Senehi, Parish Sedghizadeh   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Mixed schwannoma with meningioma of the trigeminal nerve

Indian Journal of Pathology and Microbiology, 2010
Mixed tumors composed of schwannoma and meningiomas are extremely rare and are usually associated with neurofibromatosis-2 (NF-2). So far, all the cases reported have involved the cerebello-pontine angle.
Jain Ayushi, Suri Vaishali, Sharma Bhawani, Sharma Mehar   +3 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Mixed epithelial stromal tumor of the kidney

Indian Journal of Urology, 2011
In recent years, a rare distinctive kidney tumor composed of a mixture of stroma and epithelium with solid and cystic architecture has been recognized, which has to be distinguished from other renal neoplasms.
Hariprasada D Rao, S Sriram, B H Srinivas, Sundaram Challa, Ram Reddy Ch, Pisapati Murthy   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Feasibility of multiomics tumor profiling for guiding treatment of melanoma

There is limited evidence supporting the feasibility of using omics and functional technologies to inform treatment decisions. Here we present results from a cohort of 116 melanoma patients in the prospective, multicentric observational Tumor Profiler ...
Frei, Anja, Irmisch, Anja, Baciu-Drăgan, Monica-Andreea, Ring, Alexander, Tusup, Marina, Schuerch, Manuel, Beisel, Christian, Lehmann, Kjong-Van, Gosztonyi, Benedict, Rätsch, Gunnar, Chicherova, Natalia, Bertolini, Anne, Heinzelmann, Viola, Theocharides, Alexandre, Rahimzadeh, Parisa, Bonilla, Ximena, Chevrier, Stéphane, Pelkmans, Lucas, Maass, Gerd, Lischetti, Ulrike, Dummer, Reinhard, Sivapatham, Sujana, Wicki, Andreas, Boos, Laura Amanda, Mena, Julien, Gut, Gabriele, Wollscheid, Bernd, Nowak, Marta, Toussaint, Nora Christina, Milani, Emanuela S., del Castillo, Jacobo Sarabia, Beerenwinkel, Niko, Prummer, Michael, Snijder, Berend, Goetze, Sandra, Moch, Holger, Ferreira, Pedro, Sobottka, Bettina, Casanova, Ruben, Jacobs, Alice K., Koelzer, Viktor H., Kuipers, Jack, Bacac, Marina, Miglino, Nicola, Jacob, Francis, Aebersold, Ruedi, Weller, Michael, Wegmann, Rebekka, Manz, Markus G., Mehra, Tarun, Esposito, Cinzia, Bodenmiller, Bernd, Singer, Franziska, Levesque, Mitchell P., Yu, Shuqing   +54 more
core   +1 more source

New molecular mediators in tumor angiogenesis [PDF]

, 2007
Angiogenesis is essential for tumor growth and progression. It has been demonstrated that tumor growth beyond a size 1 to 2 mm3 requires the induction of new vessels.
Jonas, Dietger, Beecken, Wolf-Dietrich, Kramer, Wolfgang   +2 more
core   +1 more source

Mixed tumor of the soft tissue (arm)

Human Pathology: Case Reports, 2014
Mixed tumor of soft tissue is extremely rare; only 15 cases have been reported in English literature. A 56-year-old man presented with a tumor in right arm. Physical examination showed a tumor measuring 3 × 3 × 3 cm of deep portion of right arm.
Tadashi Terada, MD, PhD
doaj   +1 more source