Results 61 to 70 of about 3,746,167 (305)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Tumor de colisión de cérvix uterino: presentación de 17 casos
Revista Chilena de Obstetricia y Ginecología, 2011 El tumor de colisión es una variante poco frecuente de tumores del cérvix uterino, originados de las células de reserva de la unión escamocelular y que debe ser diferenciado de los carcinomas adenoescamosos.
Ernesto García A +2 more
doaj
Uterine Malignant Mixed Mullerian Tumor (MMMT)
Indonesian Journal of Cancer, 2010 It was reported, a case of Uterine Malignant Mixed Mullerian Tumor (MMMT) in 54 years old woman who has not reached menopause with nulliparity. The patient was wrongfully diagnosed with cervical cancer earlier and on the second visit, diagnosed with ...
IMAM RASJIDI +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Somatic gene therapy for cancer. The utility of transferrinfection in generating ‘tumor vaccines’ [PDF]
, 1993 The last few years have seen the development of a branch of somatic gene therapy which aims at strengthening the immune surveillance of the body, leading to eradication of disseminated cancer tumor cells and occult micrometastases after surgical removal ...
Zatloukal, Kurt +6 more
core +1 more source
Journal of Translational Medicine, 2023 Background Accurate differentiation of pseudoprogression (PsP) from tumor progression (TP) in glioblastomas (GBMs) is essential for appropriate clinical management and prognostication of these patients.
Laiz Laura de Godoy +10 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Mixed adenoneuroendocrine carcinoma of the esophagus: A case report and review of the literature
Nigerian Journal of Surgery, 2018 The most frequent presentation of esophageal cancer is adenocarcinoma and squamous cell carcinoma. In recent years, the latter has decreased its incidence increasing the adenocarcinoma.
Fernando Mendoza-Moreno +7 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source