Results 101 to 110 of about 699,277 (302)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dispersion-shifted all-solid high index-contrast microstructured optical fiber for nonlinear applications at 1.55µm

open access: yes, 2009
We report the fabrication of an all-solid highly nonlinear microstructured optical fiber. The structured preform was made by glass extrusion using two types of commercial lead silicate glasses that provide high index-contrast.
Camerlingo, Angela   +7 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Morphology of the scattering targets: Fresnel and turbulent mechanisms, part 2.1A [PDF]

open access: yes
Refractive index fluctuations cause coherent scattering and reflection of VHF radio waves from the clear air in the altitude region between 0 and approximately 90 km. Similar echoes from the stratosphere/troposphere and the mesosphere are observed at UHF
Royrvik, O.
core   +1 more source

Noise Performance Comparison of 1.5 um Correlated Photon Pair Generation in Different Fibers

open access: yes, 2010
In this paper, the noise performances of 1.5 um correlated photon pair generations based on spontaneous four wave-mixing in three types of fibers, i.e., dispersion shifted fiber, highly nonlinear fiber, and highly nonlinear microstructure fiber are ...
Brainis   +33 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Energy Mix Concentration Index (EMCI): Methodological considerations for implementation

open access: yesMethodsX, 2019
The Energy Mix Concentration Index (EMCI) is a quantitative indicator of concentration of the energy mix based upon the Herfindahl-Hirschman Index. We use the EMCI to compare the evolution of the diversification (versus concentration) of energy mixes in the long-term in order to reveal the transformations of the energy structures which determine energy
Mar Rubio-Varas, Beatriz Muñoz-Delgado
openaire   +6 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Iron zircon pigment synthesis: Proposal of a mixing index for the raw materials mixtures

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2017
Iron zircon coral pigments are very interesting from an industrial point of view because of their high colouring power and their stability at high temperatures.
Eulalia Zumaquero   +3 more
doaj   +1 more source

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