Results 61 to 70 of about 193,007 (199)

Near-surface ocean temperature and air-sea heat flux observed by a buoy array during summer to autumn in year 2014 in the northern South China Sea

Frontiers in Marine Science
The observational data of the air-sea interface and upper ocean elements from a buoy array deployed in the northern South China Sea from June to November 2014 is analyzed.
Zixi Wu, Han Zhang, Han Zhang, Han Zhang
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Similarity Solutions of Jet Development Mixing Layers Using Algebraic and 1-Equation Turbulence Models

Acta Polytechnica, 2006
Mixing layers are formed between two parallel fluid streams having different velocities. One of the velocities may be zero, as is the usual case of the mixing layer that surrounds, immediately downstream from the nozzle, the core of a developing jet ...
V. Tesař
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A LES Study on Passive Mixing in Supersonic Shear Layer Flows Considering Effects of Baffle Configuration

Advances in Mechanical Engineering, 2014
Under the background of dual combustor ramjet (DCR), a numerical investigation of supersonic mixing layer was launched, focused on the mixing enhancement method of applying baffles with different geometric configurations.
Ren Zhao-Xin, Wang Bing
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The influence of the SAL and lightning on tropospheric ozone variability over the Northern Tropical Atlantic: Results from Cape Verde during 2010

Geophysical Research Letters, 2012
We present results for multiple Saharan Air Layer (SAL) events and their relationship to tropospheric ozone mixing ratios that were observed in the Eastern Atlantic during the summer of 2010 using ozonesondes.
Gregory S. Jenkins, Miliaritiana L. Robjhon, Jonathan W. Smith, Jonathan Clark, Luis Mendes   +4 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Contribution of extreme meteorological forcing to vertical mixing in a small, shallow subtropical lake

Journal of Limnology, 2016
Studying mixing processes in a stratified lake is important for understanding the biological, chemical and physical processes occurring there. Statistical analyses were performed of data from a small, shallow, stratified lake in a subtropical alpine ...
Nobuaki Kimura, Wen-Cheng Liu, Jeng-Wei Tsai, Chih-Yu Chiu, Timothy K. Kratz, Akira Tai   +5 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source