Results 101 to 110 of about 2,433,116 (369)

On the role of LHC and HL-LHC in constraining flavor changing neutral currents

Physics Letters B
The Standard Model has no Flavor-Changing Neutral Current (FCNC) processes at the tree level. Therefore, processes featuring FCNC in new physics are tightly constrained by data.
A.S. de Jesus, S. Kovalenko, T.B. de Melo, J.P. Neto, Y.M. Oviedo-Torres, F.S. Queiroz, Y.S. Villamizar, A.R. Zerwekh   +7 more
doaj   +1 more source

Revisiting the vector leptoquark explanation of the B-physics anomalies [PDF]

Journal of High Energy Physics, 2019
We present a thorough investigation of the vector leptoquark hypothesis for a combined explanation of the B-physics anomalies. We analyze this hypothesis from a twofold perspective, taking into account recent results from B-physics observables and high ...
C. Cornella, J. Fuentes-Martín, G. Isidori   +2 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Multi-physics Analysis Method and Conceptual Design of Helically Metallic Fuel

Yuanzineng kexue jishu
The helically metallic fuel is promising to improve the power density and safety margin of reactors core by its advantages of high thermal conductivity, large heat transfer area-to-volume ratio and continual inter-channel mixing.
GU Hanyang, XIAO Yao, CONG Tenglong, GUO Hui, FU Junsen, CAI Mengke, SONG Qufei
doaj   +1 more source

Tau and charm decays

Comptes Rendus. Physique, 2020
A summary of recent precise results in tau and charm physics is presented. Topics include leptonic and hadronic tau decays, lepton flavour and lepton number violation, charm mixing and $\mathit{CP}$ violation, leptonic and semileptonic charm decays, rare
Gersabeck, Evelina, Pich, Antonio
doaj   +1 more source

Probing New Physics in Rare Charm Processes [PDF]

, 1994
The possibility of using the charm system to search for new physics is addressed. Phenomena such as $D^0-\bar D^0$ mixing and rare decays of charmed mesons are first examined in the Standard Model to test our present understanding and to serve as ...
Hewett, J. L.
core   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

A Minimal See-Saw Model for Hierarchical Neutrino Masses with Large Mixing

, 1999
The atmospheric and solar neutrino oscillation data suggest hierarchical neutrino masses with at least one large mixing. The simplest see-saw models for reconciling the two features are U(1) extensions of the SM with flavour dependent gauge charges.
Apollonio, D.P. Roy, Fukuda, Fukuda, Gell-Mann, Ibanez, Ma, Ma, Ma, Ma, Marshak, Mohapatra, Yanagida   +12 more
core   +1 more source