Results 141 to 150 of about 2,680,157 (305)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Landcover degradation analysis of Mediterranean forest by means of hyperplanes obtained from mixture linear algorithms (MLA) [PDF]
, 2009 The percentage alteration of the Mediterranean forest landscape is one of the primary indicators for its degradation. In this sense, the land cover abundances change analysis by using mixture linear algorithms (MLA), is presented like a good alternative ...
Vázquez Sierra, José Manuel +2 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Equity Index Skew, Market Crashes and Asymmetric Normal Mixture GARCH [PDF]
The skewness in physical distributions of equity index returns and the implied volatility skew in the risk-neutral measure are subjects of extensive academic research.
Emese Lazar, Carol Alexandra
core
STRENGTH OF REACTIVE SILICA SAND POWDER CONCRETEMADE OF LOCAL POWDERS
Al-Qadisiyah Journal for Engineering Science, 2010 The main purpose of this research is to study the strength of the RPC incorporating local powders (reactive silica sand powder) and compare it with RPC incorporating condensed silica fume.
Mithaq A. Louis
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Model-based approaches to synthesize microarray data: a unifying review using mixture SEM
, 2009 A considerable amount of di®erent of approaches have been proposed for synthesizing gene expression data obtained from microarray experiments. In this paper, we have a closer look at various types of Gaussian mixture models which have recently been ...
J. K. Vermunt, MARTELLA, Francesca
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source