Results 161 to 170 of about 2,449,669 (317)

Understanding the shape of the mixture failure rate (with engineering and demographic applications) [PDF]

open access: yes
Mixtures of distributions are usually effectively used for modeling heterogeneity. It is well known that mixtures of DFR distributions are always DFR. On the other hand, mixtures of IFR distributions can decrease, at least in some intervals of time.
Maxim S. Finkelstein
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A new approach to calculate and forecast dynamic conditional correlation - the use of a multivariate heteroskedastic mixture model [PDF]

open access: yes
Much research in finance has been directed towards forecasting time varying volatility of unidimensional macroeconomic variables such as stock index, exchange rate and interest rate.
Lu, Cheng
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Wpływ formy użytkowej nikosulfuronu w mieszaninie z mezotrionem na selektywność i skuteczność eliminowania chwastów w uprawie kukurydzy

open access: yesAgronomy Science, 2015
Obniżenie fitotoksyczności herbicydów oraz poprawa efektu chwastobójczego do późnych faz rozwojowych w celu uniknięcia strat w plonie ziarna kukurydzy były założeniem podjętych badań nad działaniem mieszaniny nikosulfuronu z mezotrionem w trzech ...
HANNA GOŁĘBIOWSKA, TOMASZ SNOPCZYŃSKI
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Baysian Flexible Mixture Distribution Modelling of Dichotomous Choice Contingent Valuation with Heterogeneity [PDF]

open access: yes
This paper considers the performance of a model of mixture normal distributions for dichotomous choice contingent valuation data, which allows the researcher to consider unobserved heterogeneity across the sample.
Jorge E. Arana, Carmelo J. Leon
core  

Individual Identification of Prey in Carnivore Scats. [PDF]

open access: yesMol Ecol Resour
Eriksson CE   +4 more
europepmc   +1 more source

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