Results 161 to 170 of about 2,680,157 (305)

Developmental Switch From Elemental to Configural Processing of Odor Mixtures in Humans. [PDF]

Dev Psychobiol
Romagny S, Coureaud G, Thomas-Danguin T.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Estimation of Finite Mixture Models

, 2005
A recorded signal frequently results from the mixture of many signals from several classifiable sources. Knowledge of the contribution of the underlying sources to the recorded signal is valuable in several applications, such as remote sensing.
Rouse, David Marshall
core  

Effect of Steel Slag and Air-Cooled Blast Furnace Slag Aggregates on the Performance of Warm-Mix Asphalt Concrete Produced with Foamed Bitumen. [PDF]

Materials (Basel)
Stępień J, Maciejewski K, Ramiączek P, Chomicz-Kowalska A.   +3 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Per- and polyfluoroalkyl substances, perceived stress, and miscarriage risk in a cohort of US Black women. [PDF]

Environ Epidemiol
Schildroth S, Claus Henn B, Fruh V, Wesselink AK, Vines AI, Keil AP, Jackson CL, Jukic AM, Harmon QE, Wegienka G, Wise LA.   +10 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A Perfect Storm of Pollutants: Environmental Mixtures in the Pathogenesis of Atherosclerosis. [PDF]

Int J Mol Sci
Gorini F, Palazzo M, Simonini L, Tonacci A, Rizza A, Wu H, Minichilli F, Borghini A.   +7 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Baysian Flexible Mixture Distribution Modelling of Dichotomous Choice Contingent Valuation with Heterogeneity [PDF]

This paper considers the performance of a model of mixture normal distributions for dichotomous choice contingent valuation data, which allows the researcher to consider unobserved heterogeneity across the sample.
Jorge E. Arana, Carmelo J. Leon
core