Results 201 to 210 of about 16,235,673 (260)

scHiCSRS: a self-representation smoothing method with Gaussian mixture model for imputing single cell Hi-C data. [PDF]

BMC Bioinformatics
Xie Q, Meng W, Lin S.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Deciphering individual triticale grain weight patterns: A gaussian mixture model approach. [PDF]

PLoS One
Kim BH, Kwon H, Kim W.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A LATENT VARIABLE MIXTURE MODEL FOR COMPOSITION-ON-COMPOSITION REGRESSION WITH APPLICATION TO CHEMICAL RECYCLING. [PDF]

Ann Appl Stat
Rios N, Xue L, Zhan X.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A New Mixture Model With Cure Rate Applied to Breast Cancer Data. [PDF]

Biom J
Gallardo DI, Brandão M, Leão J, Bourguignon M, Calsavara V.   +4 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Small Scale Multi-Object Segmentation in Mid-Infrared Image Using the Image Timing Features-Gaussian Mixture Model and Convolutional-UNet. [PDF]

Sensors (Basel)
Lv M, Liu H, Wang M, Wang D, Li H, Lu X, Guo Z, Li Q.   +7 more
europepmc   +1 more source

A novel damage detection method based on sequential iteration and Gaussian mixture model for structural health monitoring under environmental effects. [PDF]

Sci Rep
Huang JZ, Yang J, Li DS, Kong WC, Wang YF.   +4 more
europepmc   +1 more source