Results 211 to 220 of about 1,286,114 (315)

Model-based Methods of Classification: Using the mclust Software in Chemometrics

Due to recent advances in methods and software for model-based clustering, and to the interpretability of the results, clustering procedures based on probability models are increasingly preferred over heuristic methods. The clustering process estimates a
Chris Fraley, Adrian Raftery
core  

BayesRare: Bayesian mixture model for population-level rare cell type detection in multi-subject single-cell RNA sequencing data. [PDF]

Brief Bioinform
Yan Y, Wu H.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Bayesian inference for Hidden Markov Model

Hidden Markov Models can be considered an extension of mixture models, allowing for dependent observations. In a hierarchical Bayesian framework, we show how Reversible Jump Markov Chain Monte Carlo techniques can be used to estimate the parameters of ...
Luisa Scaccia, Rosella Castellano
core  

A latent class pattern mixture model for nonignorable nonresponses in multivariate categorical data. [PDF]

Comput Stat
Lee J, Sieger ML, Phillips JD.
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Trends and Determinants of Smart Device Usage Among Children for Six Years: Latent Trajectory Classes Using a Growth Mixture Model. [PDF]

J Korean Med Sci
Jeon S, Lee S, Shin Y.
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Limitations of single spot urine sampling and mixture model assumptions: commentary on Feng et al.'s study of heavy metal exposure and vascular age. [PDF]

J Transl Med
Chen J, Mao L.
europepmc   +1 more source