Results 41 to 50 of about 791,274 (314)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

A Mixture Integer-Valued Garch Model

open access: yesRevstat Statistical Journal, 2016
In this paper, we generalize the mixture integer-valued ARCH model (MINARCH) introduced by Zhu et al. (2010) (F. Zhu, Q. Li, D. Wang. A mixture integer-valued ARCH model, J. Statist. Plann.
Mamadou Lamine Diop   +2 more
doaj   +1 more source

STENSL: Microbial Source Tracking with ENvironment SeLection

open access: yesmSystems, 2022
Microbial source tracking analysis has emerged as a widespread technique for characterizing the properties of complex microbial communities. However, this analysis is currently limited to source environments sampled in a specific study.
Ulzee An   +5 more
doaj   +1 more source

The VampPrior Mixture Model

open access: yesCoRR
Widely used deep latent variable models (DLVMs), in particular Variational Autoencoders (VAEs), employ overly simplistic priors on the latent space. To achieve strong clustering performance, existing methods that replace the standard normal prior with a Gaussian mixture model (GMM) require defining the number of clusters to be close to the number of ...
Andrew Stirn, David A. Knowles
openaire   +3 more sources

Testing for homogeneity in mixture models [PDF]

open access: yesEconometric Theory, 2017
Statistical models of unobserved heterogeneity are typically formalized as mixtures of simple parametric models and interest naturally focuses on testing for homogeneity versus general mixture alternatives. Many tests of this type can be interpreted asC(α) tests, as in Neyman (1959), and shown to be locally asymptotically optimal.
Jiaying Gu   +2 more
openaire   +6 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Uncovering the heterogeneity of a solar flare mechanism with mixture models

open access: yesFrontiers in Astronomy and Space Sciences
The physics of solar flares occurring on the Sun is highly complex and far from fully understood. However, observations show that solar eruptions are associated with the intense kilogauss fields of active regions, where free energies are stored with ...
Bach Viet Do   +4 more
doaj   +1 more source

A Smart Region-Growing Algorithm for Single-Neuron Segmentation From Confocal and 2-Photon Datasets

open access: yesFrontiers in Neuroinformatics, 2020
Accurately digitizing the brain at the micro-scale is crucial for investigating brain structure-function relationships and documenting morphological alterations due to neuropathies.
Alejandro Luis Callara   +5 more
doaj   +1 more source

On Methods for Merging Mixture Model Components Suitable for Unsupervised Image Segmentation Tasks

open access: yesMathematics, 2022
Unsupervised image segmentation is one of the most important and fundamental tasks in many computer vision systems. Mixture model is a compelling framework for unsupervised image segmentation.
Branislav Panić   +3 more
doaj   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

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