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MODELOS HIERÁRQUICOS BAYESIANOS PARA ESTUDAR A DISTRIBUIÇÃO ESPACIAL DA INFESTAÇÃO DA BROCA DO CAFÉ EM NÍVEL LOCAL MODELOS HIERÁRQUICOS BAYESIANOS PARA ESTUDAR A DISTRIBUIÇÃO ESPACIAL DA INFESTAÇÃO DA BROCA DO CAFÉ EM NÍVEL LOCAL MODELOS HIERÁRQUICOS BAYESIANOS PARA ESTUDIAR LA DISTRIBUCIÓN ESPACIAL DE BROCA DEL CAFÉ A NIVEL LOCAL

Revista Colombiana de Estadística, 2003
Studying the spatial distribution of agricultural pests can provide important information about the species dispersion mechanisms and its interaction with environmental factors.
Ruiz C. Ramiro, Demétrio Clarice G. B., Assunção Renato M., Leandro Roseli A.   +3 more
doaj  

Adolescent help-seeking on a psychological support hotline: latent classes, predictors, and distal outcomes

Frontiers in Psychiatry
BackgroundAdolescents who contact psychological hotlines present with diverse problems and levels of risk. Recognizing common patterns quickly can help counselors match responses to need.
Zhihua Xie, Yanhong Hu, Yueshi Ye, Yongsheng Li, Lei Li, Maozeng Yang, Zezhi Li   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Probabilistic relabelling strategies for the label switching problem in Bayesian mixture models. [PDF]

, 2010
The label switching problem is caused by the likelihood of a Bayesian mixture model being invariant to permutations of the labels. The permutation can change multiple times between Markov Chain Monte Carlo (MCMC) iterations making it difficult to infer ...
Sperrin, M.; id_orcid, Sperrin, M., Wit, Ernst, Sperrin, Matthew, Sperrin, M.,, Jaki, T.,, Jaki, T., Jaki, Thomas, Wit, E., Wit, E.,   +9 more
core   +1 more source

REBayes: An R Package for Empirical Bayes Mixture Methods

Journal of Statistical Software, 2017
Models of unobserved heterogeneity, or frailty as it is commonly known in survival analysis, can often be formulated as semiparametric mixture models and estimated by maximum likelihood as proposed by Robbins (1950) and elaborated by Kiefer and Wolfowitz
Roger Koenker, Jiaying Gu
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

EMMIXcskew: An R Package for the Fitting of a Mixture of Canonical Fundamental Skew t-Distributions

Journal of Statistical Software, 2018
This paper presents the R package EMMIXcskew for the fitting of the canonical fundamental skew t-distribution (CFUST) and finite mixtures of CFUST distributions (FMCFUST) via maximum likelihood (ML).
Sharon X. Lee, Geoffrey J. McLachlan
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A simulation study of a parametric mixture model of three different distributions to analyze heterogeneous survival data

, 2013
In this paper a simulation study of a parametric mixture model of three different distributions is considered to model heterogeneous survival data.Some properties of the proposed parametric mixture of Exponential, Gamma and Weibull are investigated.The ...
Mohammed, Yusuf Abbakar, Yatim, Bidin, Ismail, Suzilah   +2 more
core   +1 more source