Results 71 to 80 of about 1,959,808 (288)
Frontiers in PsychiatryBackgroundAdolescents who contact psychological hotlines present with diverse problems and levels of risk. Recognizing common patterns quickly can help counselors match responses to need.
Zhihua Xie +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Geodesic Finite Mixture Models [PDF]
Proceedings of the British Machine Vision Conference 2014, 2014 Peer ...
Simó Serra, Edgar +2 more
openaire +4 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
REBayes: An R Package for Empirical Bayes Mixture Methods
Journal of Statistical Software, 2017 Models of unobserved heterogeneity, or frailty as it is commonly known in survival analysis, can often be formulated as semiparametric mixture models and estimated by maximum likelihood as proposed by Robbins (1950) and elaborated by Kiefer and Wolfowitz
Roger Koenker, Jiaying Gu
doaj +1 more source
Semiparametric topographical mixture models with symmetric errors [PDF]
, 2014 Motivated by the analysis of a Positron Emission Tomography (PET) imaging data considered in Bowen et al. (2012), we introduce a semiparametric topographical mixture model able to capture the characteristics of dichotomous shifted response-type ...
Butucea, Cristina +2 more
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
EMMIXcskew: An R Package for the Fitting of a Mixture of Canonical Fundamental Skew t-Distributions
Journal of Statistical Software, 2018 This paper presents the R package EMMIXcskew for the fitting of the canonical fundamental skew t-distribution (CFUST) and finite mixtures of CFUST distributions (FMCFUST) via maximum likelihood (ML).
Sharon X. Lee, Geoffrey J. McLachlan
doaj +1 more source
Mixture-model adaptation for SMT [PDF]
Proceedings of the Second Workshop on Statistical Machine Translation - StatMT '07, 2007 We describe a mixture-model approach to adapting a Statistical Machine Translation System for new domains, using weights that depend on text distances to mixture components. We investigate a number of variants on this approach, including cross-domain versus dynamic adaptation; linear versus loglinear mixtures; language and translation model adaptation;
Foster, George, Kuhn, Roland
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source