Results 171 to 180 of about 18,715 (245)

The crystal structure of human transport and Golgi organization 2 homolog (TANGO2) suggests a cysteine N‐terminal nucleophile (Ntn) hydrolase

open access: yesActa Crystallographica Section D, Volume 82, Issue 4, Page 383-396, April 2026.
This study reports the first crystal structure of human TANGO2, mutations of which are responsible for TANGO2 deficiency disorder. The crystallographic analysis demonstrates that interactions between heme and TANGO2 are nonspecific, helping to address ongoing questions about the role of TANGO2 as a heme‐trafficking protein.Recently, there has been ...
Dayong Zhou   +3 more
wiley   +1 more source

Crystal structures of Fsc1, a novel autophagy factor that mediates autophagosome–vacuole fusion in fission yeast

open access: yesActa Crystallographica Section D, Volume 82, Issue 4, Page 358-369, April 2026.
Crystal structures of the autophagy protein Fsc1 reveal conserved fasciclin features and a stable dimer interface that illuminate its possible role as a scaffold in autophagosome–vacuole membrane fusion.Fsc1 is a recently identified autophagy factor in the fission yeast Schizosaccharomyces pombe that is implicated in the autophagosome–vacuole fusion ...
Chidiogo Azuka, Jian Liu, Xiangshu Jin
wiley   +1 more source

Die Preisverleihung: Media Literacy Award

open access: yesMedienimpulse, 2017
Katharina Kaiser-Müller
doaj  

The Impact of Community‐Based Midwife Continuity of Care Models for Women Living in Areas of Social Disadvantage and Ethnic Diversity in the United Kingdom: A Prospective Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 5, Page 958-973, April 2026.
ABSTRACT Objective Addressing inequalities in maternal and newborn health is a UK public health priority. Evidence on effective multi‐interventional strategies is urgently needed. This study evaluated the impact of community‐based midwife continuity of care (CBMCOC) models for women and babies in ethnically diverse and socially disadvantaged areas of ...
Cristina Fernandez Turienzo   +28 more
wiley   +1 more source

The 10‐year stability of three subscale scores of the Self‐Report of the Effects of Alcohol measure and their relationship to changes in drinking quantities over the same period

open access: yesAlcohol, Clinical and Experimental Research, Volume 50, Issue 4, April 2026.
The Self‐Report of the Effects of Alcohol (SRE) questionnaire records the number of drinks needed for effects across three life periods; a higher number of drinks required for effects indicates higher risks for future alcohol problems. This paper reports changes in SRE subscale scores measured five times over 10 years in 331 drinkers.
Marc A. Schuckit   +13 more
wiley   +1 more source

Decreased Severity of Oral Immunotherapy Induced Gastrointestinal Eosinophilic Reactions Following Revisions in Milk‐Treatment Protocol

open access: yesAllergy, Volume 81, Issue 4, Page 1219-1227, April 2026.
A revised milk OIT protocol with lower daily allergen load and slower dose escalation reduced the severity and delayed onset of OIT‐induced gastrointestinal eosinophilic reactions (OITIGER). Elevated baseline absolute eosinophil count (AEC > 600/μL) was a consistent independent risk factor for OITIGER, while older age was protective.
Na'ama Epstein‐Rigbi   +8 more
wiley   +1 more source

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