Results 21 to 30 of about 243 (91)

Acute and long-term cardioprotective effects of the Traditional Chinese Medicine MLC901 against myocardial ischemia-reperfusion injury in mice. [PDF]

Sci Rep, 2017
MLC901, a traditional Chinese medicine containing a cocktail of active molecules, both reduces cerebral infarction and improves recovery in patients with ischemic stroke. The aim of this study was to evaluate the acute and long-term benefits of MLC901 in
Vincent A, Covinhes A, Barrère C, Gallot L, Thoumala S, Piot C, Heurteaux C, Lazdunski M, Nargeot J, Barrère-Lemaire S.   +9 more
europepmc   +6 more sources

Positive effects of the traditional Chinese medicine MLC901 in cognitive tasks. [PDF]

J Neurosci Res, 2015
MLC901 (NurAiDII) is used as a treatment for stroke patients. It has been shown that MLC901 improves motor and cognitive recovery in ischemic and traumatic brain‐injured rodents. The present study seeks to delineate cognitive effects induced by MLC901 in
Lorivel T, Gandin C, Veyssière J, Lazdunski M, Heurteaux C.   +4 more
europepmc   +5 more sources

Effect of MLC901 on MIR30C-5P expression, TGF-Β expression, VEGF receptor expression, degree of axon demyelination and changes in neuropathic pain behaviour in experimental animals experiencing neuropathic pain with circumferential spinal stenosis method. [PDF]

Ann Med Surg (Lond), 2022
Neuropathic pain is a major problem whose pathogenesis is not known yet, which makes it difficult to treat. Effective treatment of neuropathic pain usually uses multimodal therapy that takes a long time but causes major health problems, which are ...
Priyanto B, Islam AA, Hatta M, Bukhari A, Rosyidi RM.   +4 more
europepmc   +2 more sources

Antidepressant efficacy of MLC901 in the 6-hydroxydopamine mice model of Parkinson’s disease [PDF]

Physiology and Pharmacology, 2021
1. Department of Biology, Faculty of Sciences, University of Zanjan, Zanjan, Iran 2. Department of Biology, Faculty of Science, Gonbad Kavous University, Gonbad Kavous, Iran 3.
Mohaddeseh Ebrahimi-Ghiri, Sakineh Alijanpour, Fatemeh Khakpai, M. Zarrindast   +3 more
semanticscholar   +2 more sources

Mechanical scratch injury on differentiated motor neuron of NSC-34 cells as an in vitro model for evaluation of neuroregeneration potential of NeuroAiD II (MLC901). [PDF]

In Vitro Model
Anjum A, Yazid MD, Daud MF, Idris J, Ng AMH, Naicker AS, Ismail OH, Athi Kumar RK, Lokanathan Y.   +8 more
europepmc   +3 more sources

The potential of MLC901 as adjuvant therapy for traumatic spinal cord injury by multi-pathway biomechanism: a systematic review

Bali Medical Journal, 2023
Background: Traumatic spinal cord injury (tSCI) is a severe neurological condition that causes long-term nerve function impairment and can even cause death. Further efforts are needed to find better therapy for this condition to improve patients' quality
Putu Wisnu Wardhana, Agung B S Satyarsa, Rohadi Muhammad Rosyid, Husni Harmansyah, T. Mahadewa, A. Islam, I. M. Jawi, Sri Maliawan   +7 more
semanticscholar   +2 more sources

Effects of Moleac 901 after severe spinal cord injury on chronic phase in Wistar rats [PDF]

Heliyon
Background: MLC901 is a phytopharmaceutical comprising significant compounds that can induce microenvironments conducive to the proliferation and specialization of neural cell progenitors.
Dewa Putu Wisnu Wardhana, Sri Maliawan, Tjokorda Gde Bagus Mahadewa, Andi Asadul Islam, I Made Jawi, Anak Agung Wiradewi Lestari, I Gusti Kamasan Nyoman Arijana, Rohadi Muhammad Rosyidi, Sinta Wiranata   +8 more
doaj   +2 more sources

A Review of NeuroAiDTM II (MLC901) Development in Alzheimer’s Disease Treatment: Promises of A Multimodal Pathway

Journal of Neurology Research Reviews & Reports, 2022
Background: Alzheimer’s disease (AD) is a clinical and economic burden on society. Without new treatment, the impact of AD on society could triple by 2050.
M. Dib, E. Ampil, Hoo Fan Kee, Y. Krespi, Akram Al Mahdawi, S. Ogun, H. Pakdaman, K. Rejdak   +7 more
semanticscholar   +2 more sources

MLC901 Favors Angiogenesis and Associated Recovery after Ischemic Stroke in Mice [PDF]

Cerebrovascular Diseases, 2016
Background: There is increasing evidence that angiogenesis, through new blood vessel formation, results in improved collateral circulation and may impact the long-term recovery of patients.
C. Gandin, C. Widmann, M. Lazdunski, C. Heurteaux   +3 more
semanticscholar   +3 more sources

Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol [PDF]

Stroke and Vascular Neurology
Background MLC1501, consisting of four herbs, that is, Radix Astragali, Radix Angelicae sinensis, Rhizoma Chuanxiong, Radix Polygalae, has the same pharmacological properties as its precursors MLC601 and MLC901 which contain extracts of nine herbs and ...
Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham   +12 more
doaj   +2 more sources