Results 21 to 30 of about 15,978 (252)

An in silico approach to identify early damage biomarker candidates in metachromatic leukodystrophy

Molecular Genetics and Metabolism Reports, 2023
Metachromatic leukodystrophy (MLD) is a rare, autosomal recessive lysosomal storage disease. Deficient activity of arylsulfatase A causes sulfatides to accumulate in cells of different tissues, including those in the central and peripheral nervous ...
Jessica Gómez, Laura Artigas, Raquel Valls, Javier Gervas-Arruga   +3 more
doaj   +1 more source

Tubular Discectomy Versus Conventional Microdiscectomy for the Treatment of Lumbar Disc Herniation: A Comparative Study [PDF]

Journal of Minimally Invasive Spine Surgery and Technique, 2020
Objective The study aims to compare the outcomes of micro-lumbar discectomy (MLD) with tubular micro-endoscopic discectomy (MED). Methods A retrospective analysis of 414 patients who underwent single-level lumbar discectomy either by tubular MED or MLD ...
Sanjeev Asati, Sanyam Jain, Vishal G Kundnani   +2 more
doaj   +1 more source

Comparative study of microsurgical lumbar discectomy and percutaneous endoscopic lumbar discectomy based on clinical outcome and muscle injury markers [PDF]

Journal of Krishna Institute of Medical Sciences University, 2023
Background: Lumbar Disc Herniation (LDH) is the most frequent entity affecting the spine resulting in low back pain and sciatica. Many minimally invasive procedures have been proposed for the treatment of LDH. Percutaneous Endoscopic Discectomy (PELD) is
Gautham Hanu, Silpa Thota, Venkat K, Ramesh Chandra V V, BCM Prasad, Siva Kumar Reddy, Geetanvita N , Indupriya E   +7 more
doaj   +2 more sources

Insights into the natural history of metachromatic leukodystrophy from interviews with caregivers

Orphanet Journal of Rare Diseases, 2019
Background and methods Metachromatic leukodystrophy (MLD) is a rare, autosomal recessive lysosomal storage disease caused by deficient activity of arylsulfatase A.
Magdalena Harrington, Diane Whalley, James Twiss, Rebecca Rushton, Susan Martin, Lynn Huynh, Hongbo Yang   +6 more
doaj   +1 more source

Learner-generated drawings by students with mathematical learning difficulties in finishing open number sentences

Jurnal Elemen, 2022
Although MLD students do not have good mathematical performance in completing addition and subtraction operations of integers, MLD students have suggestive ideas in the form of drawings produced in solving open number sentences questions. This study aims
Mohammad Faizal Amir
doaj   +1 more source

Distinct, Depth-Stratified Communities of Heterotrophic, Mixotrophic, and Parasitic Dinoflagellates and Ciliates in the Subarctic Northeast Pacific Euphotic Zone. [PDF]

J Eukaryot Microbiol
ABSTRACT Dinoflagellates and ciliates are important grazers of primary production in the Northeast Pacific but knowledge of their taxonomic composition and depth‐distribution is limited. These organisms also display a variety of heterotrophic feeding modes including heterotrophy, mixotrophy, and parasitism.
Jones EL, Rubin E, Rettig M, McNair H, Menden-Deuer S, Rynearson TA.   +5 more
europepmc   +2 more sources

Identification of neurodegeneration indicators and disease progression in metachromatic leukodystrophy using quantitative NMR‐based urinary metabolomics

JIMD Reports, 2022
Metachromatic leukodystrophy (MLD) is a lysosomal storage disease caused by a deficiency of the arylsulfatase A (ARSA). ARSA deficiency leads to an accumulation of sulfatides primarily in the nervous system ultimately causing demyelination. With evolving
Lucia Laugwitz, Laimdota Zizmare, Vidiyaah Santhanakumaran, Claire Cannet, Judith Böhringer, Jürgen G. Okun, Manfred Spraul, Ingeborg Krägeloh‐Mann, Samuel Groeschel, Christoph Trautwein   +9 more
doaj   +1 more source

Observed Relative Contributions of Anomalous Heat Fluxes and Effective Heat Capacity to Sea Surface Temperature Variability

Geophysical Research Letters, 2023
Sea surface temperatures (SSTs) vary not only due to heat exchange across the air‐sea interface but also due to changes in effective heat capacity as primarily determined by mixed layer depth (MLD).
Naoya Takahashi, Kelvin J. Richards, Niklas Schneider, Malte F. Stuecker, Hariharasubramanian Annamalai, Masami Nonaka   +5 more
doaj   +1 more source

The burden of disease in metachromatic leukodystrophy: results of a caregiver survey in the UK and Republic of Ireland

Orphanet Journal of Rare Diseases
Background Metachromatic Leukodystrophy (MLD) is a rare, autosomal recessive lysosomal storage disease characterised by the progressive loss of motor function and severe decline in cognitive function.
Sophie Thomas, Alexandra Morrison, Georgina Morton, Pat Roberts, Vivienne Clark, Jackie Imrie   +5 more
doaj   +1 more source

Electro‐Chemo‐Mechanical Coupling in Hf0.5Zr0.5O2 Ferroionic Heterostructures

Advanced Functional Materials, EarlyView.
Schematic of a ferroionic HZO heterostructure where epitaxial interfaces enable dynamic oxygen‐vacancy exchange, coupling ionic and ferroelectric degrees of freedom. Vacancy‐mediated polarization modulation biases HZO polymorphism, suppresses leakage, and enhances piezoelectric response, yielding distinct butterfly‐loop evolution and diode‐like ...
Achilles Bergne, Denis Alikin, Milica Vasiljevic, Victor B. Tinti, Javier Zamudio‐García, Leonardo Soares de Oliveira, Megan Landberg, Dimitrios Koukoulis, Huaiyu Chen, Jesper Wallentin, David Marrero‐López, Astri Bjørnetun Haugen, Sizhao Huang, Dennis Christensen, Nini Pryds, Alexander Tselev, Andrei Kholkin, Vincenzo Esposito   +17 more
wiley   +1 more source