Results 31 to 40 of about 32,374 (267)
Scientific Reports, 2023 Endovascular treatment is widely used in acute cerebral infarction (ACI), but patient prognosis varies greatly. We aimed to investigate the predictive value of midline shift (MLS) threshold for the clinical prognosis of patients with ACI who undergo ...
Xiao-Min Xu, Hao Zhang, Ren-Liang Meng
doaj +1 more source
Objective ML: An effective object-oriented extension to ML [PDF]
Theory and Practice of Object Systems, 1998 Objective ML is a small practical extension to ML with ob- jects and top level classes. It is fully compatible with ML; its type system is based on ML polymorphism, record types with polymorphic access, and a better treatment of type abbreviations. Objective ML allows for most fea- tures of object-oriented languages including multiple in- heritance ...
Didier Rémy, Jerome Vouillon
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Journal of Applied Mathematics, 2018 We provide a theoretical framework to study how criminal behaviors can be treated as an infectious phenomenon. There are two infectious diseases like models that mimic the role of convicted criminals in contaminating individuals not yet engaged in the ...
Silvia Martorano Raimundo +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Veterinary Sciences, 2021 Porcine circovirus 2 (PCV2), considered one of the most globally important porcine pathogens, causes postweaning multisystemic wasting syndrome (PMWS). This virus is localized in the mitochondria in pigs with PMWS. Here, we identified, for the first time,
Wanting Yu +9 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Frontiers in Neurology, 2023 BackgroundMidline shift (MLS) is troublesome problem that may occur in patients with a large infarct core (LIC) and may be related to the baseline infarct core volume.
Ting-yu Yi +13 more
doaj +1 more source
Journal of Symbolic Computation, 1989 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source