Results 81 to 90 of about 16,849 (282)

Transient analysis of FGM plates bending under thermal loading: comparative study within classical and generalized thermoelasticity

open access: yesMATEC Web of Conferences, 2019
In the classical thermoelasticty, there is coupling between thermal and elastic fields, in general, but the elastic and thermal excitations spread according to physically different laws.
Sator Ladislav   +2 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A hybrid numerical method for multi-domain wave propagation problems

open access: yesResults in Applied Mathematics
This study introduces a hybrid numerical methodology designed to address multi-domain wave propagation problems. The temporal discretization is achieved using the Houbolt scheme, a finite-difference-based approach known for its robust stability in time ...
Zihui Yan   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Solution of Elasto-Statics Problems Using the Element-Free Galerkin Method with Local Maximum Entropy Shape Functions [PDF]

open access: yes
The element free Galerkin method (EFGM) [1] is one of the most robust meshless methods for the solution of elasto-statics problems. In the EFGM, moving least squares (MLS) shape functions are used for the approximation of the field variable.
Augarde, Charles, Ullah, Zahur
core  

Oriented tensor reconstruction: tracing neural pathways from diffusion tensor MRI [PDF]

open access: yes, 2002
In this paper we develop a new technique for tracing anatomical fibers from 3D tensor fields. The technique extracts salient tensor features using a local regularization technique that allows the algorithm to cross noisy regions and bridge gaps in the ...
Barr, Alan H., Zhukov, Leonid
core  

Exciton states in monolayer MoSe2: impact on interband transitions

open access: yes, 2015
We combine linear and non-linear optical spectroscopy at 4K with ab initio calculations to study the electronic bandstructure of MoSe2 monolayers. In 1-photon photoluminescence excitation (PLE) and reflectivity we measure a separation between the A- and ...
Amand, T.   +9 more
core   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

LM-valued equalities, LM-rough approximation operators and ML-graded ditopologies

open access: yesHacettepe Journal of Mathematics and Statistics, 2017
We introduce a certain many-valued generalization of the concept of an $L$-valued equality called an $L^M$-valued equality. Properties of $L^M$-valued equalities are studied and a construction of an $L^M$-valued equality from a pseudo-metric is presented.
Alexander Sostak, Aleksandrs Eckins
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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