Results 61 to 70 of about 584,670 (289)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Application of Moving Kriging Shape Functions on Plate Problems

open access: yesNUST Journal of Engineering Sciences, 2008
The Moving Kriging (MK) interpolation was recently proposed as a superior substitution of the Moving Least Square (MLS) approximation in the construction of shape functions for the Element-Free Galerkin Method (EFGM).
Shazim Ali Memon   +2 more
doaj   +1 more source

Percepción de los docentes ecuatorianos sobre la inclusión de estudiantes sordos en la escuela regular [PDF]

open access: yes, 2023
International educational practice is oriented towards the inclusion of deaf students in regular school classrooms. In Ecuador, according to current regulations, deaf people can access special or regular schools.
Higuera Aguirre, Edison   +2 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Neurocreatividad: Análisis y enseñanza del pensamiento creativo [PDF]

open access: yes, 2022
The creative process is linked to brain activity. This process is understood as an "ability to create" as opposed to the notion of innovation that focuses on the "action of creating".
Sanz Peinado, Rocío
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Analysis of Piezoelectric Semiconducting Solids by Meshless Method

open access: yesJournal of Mechanical Engineering, 2015
In this paper, a meshless local Petrov-Galerkin (MLPG) method is proposed to calculate mechanical and electrical responses of three-dimensional piezoelectric semiconductors under static load.
Staňák P., Sládek J., Sládek V.
doaj   +1 more source

¿Existe relación entre las estrategias de aprendizaje y la lectura crítica? [PDF]

open access: yes, 2023
The development of Critical Reading and the acquisition of Learning Strategies in the student will allow him to infer, analyze and create his own meanings, thus awakening his reflective and metacognitive attitude; Fundamental elements in the teaching ...
Caballero Cervantes, Naileth
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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