Results 71 to 80 of about 3,296,150 (267)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Incorporation of Satellite Data and Uncertainty in a Nationwide Groundwater Recharge Model in New Zealand

open access: yesRemote Sensing, 2018
A nationwide model of groundwater recharge for New Zealand (NGRM), as described in this paper, demonstrated the benefits of satellite data and global models to improve the spatial definition of recharge and the estimation of recharge uncertainty.
Rogier Westerhoff   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

3D Bioprinting of Cultivated Meat Followed by the Development of a Fine-Tuned YOLO Model for the Detection and Counting of Lipoblasts, Fibroblasts, and Myogenic Cells

open access: yesFrontiers in Bioscience-Landmark
Background: Cultured meat holds significant potential as a pivotal solution for producing safe, sustainable, and high-quality protein to meet the growing demands of the global population.
Rozaliia Nabiullina   +7 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Efeito do preparo de solo e de técnicas de plantio na composição botânica e biomassa de plantas daninhas no abacaxizeiro

open access: yesPesquisa Agropecuária Gaúcha, 2006
As recomendações para controlar plantas daninhas no abacaxizeiro são feitas para solos preparados convencional- mente, mas o uso de outros preparos afeta a flora daninha e a recomendação de herbicidas.
Nelson Sebastião Model   +2 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Cobalt cationic sites in ferrierites: QM/MM modeling

open access: yesCatalysis Today, 2008
Abstract Cobalt(II) sites in ferrierites are already well-known from their catalytic activity, their speciation and properties, however, the knowledge are far from completeness. The following paper presents the first in literature combined QM/MM study to elucidate the structure of these sites.
Banach, Ewa   +4 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Optimal Grazing Exclusion Duration to Enhance Soil Carbon Sequestration in Degraded Grasslands

open access: yesAdvanced Science
Soil organic carbon (SOC) plays a crucial role in mitigating climate change and ensuring food security. Grazing exclusion (GE) is widely recognized as an effective strategy for restoring degraded grasslands and enhancing SOC sequestration, yet the ...
Bin Zhang   +9 more
doaj   +1 more source

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