Results 1 to 10 of about 189,462 (274)

Role of Matrilysins (MMP-7, MMP-26) and Stromelysins (MMP-3, MMP-10) in Diagnosing Cervical Cancer Patients [PDF]

Biomedicines
Background/Objectives: Detection of cervical lesions is crucial for effective prevention and treatment. Therefore, the search for new diagnostic markers is extremely important.
Ewa Gacuta, Michał Ławicki, Hanna Grabowska, Paweł Ławicki, Monika Kulesza, Aleksandra Kicman, Monika Zajkowska, Piotr Laudański, Sławomir Ławicki   +8 more
doaj   +2 more sources

Serum MMP‐3 and its association with central arterial stiffness among young adults is moderated by smoking and BMI [PDF]

Physiological Reports, 2021
Central arterial stiffness is an independent predictor of cardiovascular disease. It is characterized by a marked reduction in the elastin‐collagen ratio of the arterial wall extracellular matrix (ECM), and is largely the result of degradation of various
Nathaniel J. Iannarelli, Adam J. MacNeil, Kylie S. Dempster, Terrance J. Wade, Deborah D. O’Leary   +4 more
doaj   +2 more sources

Association of the MMP-3, MMP-9 and MMP-12 gene polymorphisms with COPD risk: a meta-analysis [PDF]

Archives of Medical Science, 2021
Introduction Given the evidence that the matrix metalloproteinases (MMPs) play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD), a number of case-control studies have attempted to assess the relationship between ...
Hua Zhao, Xiao-Hong Jiang, Qiu-Pin Huang, Min-Li Chen, Zheng-Fu Xie   +4 more
doaj   +2 more sources

Matrix metalloproteinases (MMP) 3 and 9 as biomarkers of severity in COVID-19 patients [PDF]

Scientific Reports, 2022
The molecular basis of the wide clinical heterogeneity of Coronavirus disease 2019 (COVID-19) is still unknown. Matrix metalloproteinases (MMPs) may have a role in the lung damage and regeneration that occur in severe patients.
Monica Gelzo, Sara Cacciapuoti, Biagio Pinchera, Annunziata De Rosa, Gustavo Cernera, Filippo Scialò, Marika Comegna, Mauro Mormile, Gabriella Fabbrocini, Roberto Parrella, Gaetano Corso, Ivan Gentile, Giuseppe Castaldo   +12 more
doaj   +2 more sources

Adenosine inhibits TNFα-induced MMP-3 production in MH7A rheumatoid arthritis synoviocytes via A2A receptor signaling [PDF]

Scientific Reports, 2022
Adenosine causes the anti-inflammatory effect of MTX; however, the contributions of synoviocyte adenosine receptors (AdoRs) are unknown, and matrix metalloproteinase 3 (MMP-3) is released by fibroblast-like synoviocytes in response to inflammatory ...
Hiroe Konishi, Shun-En Kanou, Rika Yukimatsu, Mizuki Inui, Motoya Sato, Naruto Yamamoto, Masayoshi Nakano, Masahiro Koshiba   +7 more
doaj   +2 more sources

Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis

Bone & Joint Research, 2023
Aims: Rheumatoid arthritis (RA) is a common chronic immune disease. Berberine, as its main active ingredient, was also contained in a variety of medicinal plants such as Berberaceae, Buttercup, and Rutaceae, which are widely used in digestive system ...
Zhiqi Li, Meilin Chen, Zhaoyi Wang, Qiqi Fan, Zili Lin, Xiaoyu Tao, Jiarui Wu, Zhenquan Liu, Ruichao Lin, Chongjun Zhao   +9 more
doaj   +1 more source

Macrophage Migration Inhibitory Factor Promotes Expression of Matrix Metalloproteinases 1 and 3 in Spinal Cord Astrocytes following Gecko Tail Amputation

Journal of Integrative Neuroscience, 2023
Background: The matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that play a variety of physiological and pathological roles in development, remodeling of tissues and diseases, mainly through degradation of various components of the ...
Haijun Zhang, Chunshuai Sun, Bingqiang He, Xingyuan Zhang, Huifei Hao, Yuxuan Hou, Aicheng Li, Yongjun Wang, Yingjie Wang   +8 more
doaj   +1 more source

Peanut (Arachis hypogaea) Shells Extract and Apis dorsata Honey Reduce Matrix Metalloproteinase-3 in Monosodium Iodoacetate-Induced Osteoarthritic Rats

Journal of Biomedicine and Translational Research, 2020
Background: Osteoarthritis is the most common degenerative joint disease worldwide but its treatment can cause serious adverse events. Ethanol extract of peanut shells contains luteolin functioned as its main anti-inflammatory and chondroprotective agent.
Bella Stevanny, Tungki Pratama Umar, Junoretta Haviva Ernanto, Rachmat Hidayat   +3 more
doaj   +1 more source

MMP-3 deficiency alleviates endotoxin-induced acute inflammation in the posterior eye segment [PDF]

, 2016
Matrix metalloproteinase-3 (MMP-3) is known to mediate neuroinflammatory processes by activating microglia, disrupting blood-central nervous system barriers and supporting neutrophil influx into the brain. In addition, the posterior part of the eye, more
Becker, Claude Libert, De Vos, Eichler, Evy Lefevere, Fuentes, Gearing, Goureau, Hoekzema, Hoekzema, Inge Van Hove, Jurgen Sergeys, Kaplanski, Kyriakis, Lies De Groef, Lieve Moons, Manuel Salinas-Navarro, Nemzek, Noble, Planck, Roosmarijn Vandenbroucke, Russ, Sudharshan, Suzuki, Tuaillon, Yadav, Zech   +26 more
core   +5 more sources

Changes in Cartilage Biomarker Levels During a Transcontinental Multistage Footrace Over 4486 km [PDF]

, 1978
Cartilage turnover and load-induced tissue changes are frequently assessed by quantifying concentrations of cartilage biomarkers in serum. To date, information on the effects of ultramarathon running on articular cartilage is scarce.; Serum ...
Mündermann, Annegret, Klenk, Christopher, Billich, Christian, Nüesch, Corina, Pagenstert, Geert, Schmidt-Trucksäss, Arno, Schütz, Uwe   +6 more
core   +3 more sources