Results 81 to 90 of about 991,080 (294)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Revista Facultad de Ingeniería Universidad de Antioquia, 2003 Los drenajes ácidos de mina (DAM) son lixiviados resultantes de la explotación minera de carbón, presentan bajos pH y altas concentraciones de metales pesados que los convierten en fuertes contaminantes.
Andrea Díaz +6 more
doaj
Three resurrected species of the genus Bulbothrix Hale (Parmeliaceae, Lichenized Fungi) [PDF]
Mycosphere, 2012 Bulbothrix laeviuscula, B. pseudocoronata and B. subscortea are proposed as new combinations in the Parmeliaceae based on type studies. Descriptions are presented and their characters discussed.
Benatti MN
doaj
Abortion - a philosophical perspective
Curationis, 2001 The central issue in the abortion debate is the moral status of the conceptus. There are two positions that argue this issue. At one extreme are the views of the pro-life group which argues that human life begins at the moment of conception whilst at the
MN Jali
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
AIA Avances en Investigación Agropecuaria, 2006 El melón Cantaloupe (Cucumis melo L.) es una hortaliza muy importante; sin embargo, aún no se cuenta con una guía para el manejo de la fertilización nitrogenada y la humedad del suelo que permita mantener un estado nutrimental adecuado y se refleje ...
M. R. Cigales-Rivero +2 more
doaj
Ekonomi Sharî‘ah dan Ketidakadilan Kapitalisme Global
Islamica: Jurnal Studi Keislaman, 2014 This paper understands that the Sharî‘ah Economics is a serious contender for the modern global capitalistic economic system. Capitalism has been responsible for the collapse of not only the global economic system but also the moral deterioration of ...
MN Harisudin
doaj +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source