Results 221 to 230 of about 138,791 (334)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 6, Page 1271-1287, March 2026.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

HoloMoA: a holography and deep learning tool for the identification of antimicrobial mechanisms of action and the detection of novel MoA. [PDF]

open access: yesFront Microbiol
Sedaghat Z   +10 more
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of Pseudo‐Natural Products Inspired by Aryloctahydroindole Alkaloids

open access: yesChemMedChem, Volume 21, Issue 3, 12 February 2026.
Mesembrine alkaloid pseudo‐natural products were synthesized employing a microwave‐assisted Diels–Alder reaction as a key step. Morphological profiling by cell painting revealed compound‐topology‐dependent mitochondrial fragmentation or inhibition of respiration.
Luca C. Greiner   +6 more
wiley   +1 more source

Cluster-Engineered Titanium Metal-Organic Aerogels as Tunable Platforms for Post-synthetic Doping and Enhanced Photocatalytic Hydrogen Production. [PDF]

open access: yesInorg Chem
Luengo N   +7 more
europepmc   +1 more source

Genomic support for a moa-tinamou clade and adaptive morphological convergence in flightless ratites.

open access: yesMolecular biology and evolution, 2014
A. Baker   +3 more
semanticscholar   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, Volume 16, Issue 2, Page 243-251, February 2026.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

An extremely low-density human population exterminated New Zealand moa

open access: yesNature Communications, 2014
R. Holdaway   +5 more
semanticscholar   +1 more source

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