Results 51 to 60 of about 58,944 (350)

Mode of Action (MOA) Assignment Classifications for Ecotoxicology: An Evaluation of Approaches.

Environmental Science and Technology, 2017
The mode of toxic action (MOA) is recognized as a key determinant of chemical toxicity and as an alternative to chemical class-based predictive toxicity modeling.
A. Kienzler, M. Barron, S. Belanger, A. Beasley, M. Embry   +4 more
semanticscholar   +1 more source

Extinction of the Moa [PDF]

Nature, 1871
THE very interesting article on the Moa in your issue of July 6th by Dr. Hector adds considerably to the facts already ascertained as to its existence along with man, and also as to the probability of its recent disappearance. Visiting in 1866 and 1867 many of the places mentioned by the Doctor in the Middle Island, I had opportunities of seeing ...
openaire   +2 more sources

Moa-HCl-1

, 2015
Moa HCl extraction run #1 on Orbitrap ...
Schweitzer, Mary Higby, Schroeter, Elena R., Elena R. Schroeter (619011), Mary Higby Schweitzer (2541436), Timothy P. Cleland (333266), Cleland, Timothy P.   +5 more
core   +1 more source

Interpretation of a short-term anomaly in the gravitational microlensing event MOA-2012-BLG-486 [PDF]

, 2013
D.M.B., M.D., K.H., M.H., S.I., C.S., R.A.S., and Y.T. are supported by NPRP grant NPRP-09-476-1-78 from the Qatar National Research Fund (a member of Qatar Foundation). K.H.
Koshimoto, N., Donatowicz, J., Kane, S. R., Jung, Y., BOZZA, Valerio, Shin, I., D. Dominis Prester, Gould, A., J. C. Yee, Bennett, D., Saito, To., Coutures, C., Bramich, D. M., Horne, K., Williams, Andrew, Kains, N., Gaudi, B., S. R. Kane, Hwang, K.H., H. Park, Harris, P., Kubas, D., Abe, F., Y. Muraki, Lee, C. -U., N. Koshimoto, Williams, A., P. Meintjes, D. P. Bennett, Matsubara, M., Choi, J.-Y., Martin, R., DePoy, D., Lee, C.-U., Yee, J. C., Tsapras, Y., T. Sumi, Kane, S., J. B. Marquette, A. Williams, Saito, T., D. Fukunaga, K. Ohnishi, J. Menzies, Albrow, M. D., I. G. Shin, Coutures, Ch., D. Suzuki, Batista, V., Corrales, E., J. P. Beaulieu, M. Freeman, Prester, D., J. Y. Choi, K. Wada, Sumi, T., J��rgensen, U. G., Park, H., Browne, P., J. Donatowicz, A. Gould, Dominis Prester, D., R. A. Street, Sullivan, D. J., Pogge, R., Andrade de Almeida, L., P. Fouqué, Pollard, K. R., P. J. Tristram, Suzuki, D., Rattenbury, N. J., Snodgrass, Colin, Beaulieu, J.-P., M. D. Albrow, DePoy, D. L., Brillant, S., Cole, A., P. C. M. Yock, M. Dominik, I. A. Bond, F. Abe, Gaudi, b.S., Y. Itow, Ipatov, S., N. Kains, Han, C., Pogge, R. W., S. Namba, de Almeida, L. Andrade, U. G. Jørgensen, Bachelet, E., Kavka, A., A. Yonehara, C. H. Ling, S. Ipatov, Yonehara, A., I. A. Steele, K. H. Hwang, Beaulieu, J. -P., Y. Matsubara, D. Wouters, R. W. Pogge, Lee, C., A. Cassan, N. Yamai, R. Martin, Rattenbury, N., Kains, Noé, B. S. Gaudi, D. M. Bramich, Hwang, K. -H., Shin, I.-G., K. Horne, Tristram, P. J., Hwang, K., Caldwell, J. A. R., de Andrade Almeida, L., Y. K. Jung, Jablonski, F., W. L. Sweatman, A. Fukui, P. Browne, Fukui, A., Muraki, Y., Dieters, S., L. Andrade de Almeida, Namba, S., Albrow, M., Fouqué, P., D. Kubas, Sweatman, W., A. Kavka, Bozza, V., M. Hundertmark, The Collaboration, M., Masuda, K., Menzies, J., Gaudi, B. S., Pollard, K., Yamai, N., C.h. Coutures, Dong, S., Shin, I. -G., D. J. Sullivan, J. A. R. Caldwell, K. R. Pollard, Cirrakes, E., Botzler, C. S., Subo Dong, Y. Tsapras, Sullivan, D., Ling, C., Wouters, D., Hwang, K.-H., Caldwell, J., Cassan, A., Greenhill, J., Hundertmark, M., Yock, P., Beaulieu, J.P., Choi, J.Y., Freeman, M., Chote, P., P. Chote, Marquette, J.-B., Street, R. A., Choi, J., P. Harris, Street, R., Steele, I. A., N. J. Rattenbury, Jorgensen, U., V. Batista, S. Brillant, Ohnishi, K., Meintjes, P., Jørgensen, Uffe Gråe, C. Snodgrass, Bond, I. A., Jung, Y. K., F. Jablonski, K. Masuda, Bond, I.A., Botzler, C., Beaulieu, J., Jørgensen, U. G., Dominik, M., S. Dieters, Matsubara, Y., Yock, P. C. M., Snodgrass, C., E. Corrales, Bennett, D. P., Itow, Y., Wada, K., C. Han, T.o. Saito, Choi, J. -Y., E. Bachelet, Yee, J., Marquette, J., Marquette, J. -B., J. Greenhill, Ling, C. H., Tristram, P., Sweatman, W. L., A. Cole, C. U. Lee, Bond, I., D. L. DePoy, Fouqu��, P., Bramich, D., Dong, Subo, C. S. Botzler, Fukunaga, D., Steele, I.   +215 more
core   +1 more source

Spiro‐Phenothiazine Hole‐Transporting Materials: Unlocking Stability and Scalability in Perovskite Solar Cells

Advanced Materials, EarlyView.
Fluorene‐functionalized spiro‐phenothiazine (PTZ‐Fl) exhibits strong Li+ affinity and thermal stability, enabling a PCE of 25.75% in small‐area cells and 22.07% in 25 cm2 modules. Under ISOS‐L3 conditions, PTZ‐Flbased devices retain over 80% efficiency after 1000 hours, demonstrating superior stability and scalability compared to spiro‐OMeTAD for next ...
Javier Urieta‐Mora, Seung Ju Choi, Jaeki Jeong, Silvia Orecchio, Inés García‐Benito, Manuel Pérez‐Escribano, Joaquín Calbo, Likai Zheng, Minseop Byun, Seyeong Song, Gi‐Hwan Kim, Shaik M. Zakeeruddin, Seog‐Young Yoon, Yimhyun Jo, Agustín Molina‐Ontoria, Enrique Ortí, Nazario Martín, Michael Grätzel   +17 more
wiley   +1 more source

Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1,4‐dioxane

Regulatory toxicology and pharmacology : RTP, 2017
Previous work has shown that the weight of evidence supports the hypothesis that 1,4‐dioxane causes liver tumors in rodents through cytotoxicity and subsequent regenerative hyperplasia.
M. Dourson, J. Higginbotham, Jeff Crum, H. Burleigh-Flayer, P. Nance, Norman D Forsberg, M. Lafranconi, J. Reichard   +7 more
semanticscholar   +1 more source

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

Advanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu, Chenhui Han, Cheng Xue, Manyi Sun, Bobo Song, Yongsong Xue, Guangyan Yang, Shaozhuo Xu, Wei Wei, Jiaming Li, Runze Wang, Jun Wu   +11 more
wiley   +1 more source

Mother optimization algorithm: a new human-based metaheuristic approach for solving engineering optimization

Scientific Reports, 2023
This article’s innovation and novelty are introducing a new metaheuristic method called mother optimization algorithm (MOA) that mimics the human interaction between a mother and her children.
Ivana Matoušová, Pavel Trojovský, Mohammad Dehghani, Eva Trojovská, Juraj Kostra   +4 more
doaj   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

Advanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng, Peipei Wang, Pengfei Wang, Jiamin Wang, Baiyang Li, Daqing Fang, Jian He, Xiaobei Hu, Weijuan Kan, Yubo Zhou, Chunpu Li, Jia Li, Hong Liu   +12 more
wiley   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source