Results 71 to 80 of about 83,177 (340)

Developmental Characteristics of the Embryonic Liver Tissue and Long‐Term Culture of Primary Hepatocytes in Duck

Animal Research and One Health, EarlyView.
Liver development was investigated at different embryonic ages (EAs). Furthermore, numerous hepatocyte media were formulated and evaluated. These results could elaborate the developmental characteristics of duck liver tissue and determine the most suitable medium for the proliferation and characteristic maintenance of hepatocytes in vitro, which would ...
Jie Wei, Jing Tang, Bo Zhang, Chenchen Du, Yunsheng Zhang, Ming Xie, Zhengkui Zhou, Shuisheng Hou   +7 more
wiley   +1 more source

MOA-2010-BLG-353Lb: A Possible Saturn Revealed [PDF]

, 2015
We report the discovery of a possible planet in microlensing event MOA-2010-BLG353. This event was only recognised as having a planetary signal after the microlensing event had nished, and following a systematic analysis of all archival data for binary ...
N. Rattenbury, D. P. Bennett, T. Sumi, N. Koshimoto, I. Bond, A. Udalski, F. Abe, A. Bhattacharya, M. Freeman, A. Fukui, Y. Itow, M.-C.-A. Li, C.-H. Ling, K. Masuda, Y. Matsubara, Y. Muraki, K. Ohnishi, T. Saito, A. Sharan, D. Sullivan, D. Suzuki, P. Tristram, S. Kozłowski, P. Mróz, P. Pietrukowicz, G. Pietrzyński, R. Poleski, D. Skowron, J. Skowron, I. Soszy'nski, M. K. Szymański, K. Ulaczyk, Ł. Wyrzykowski   +32 more
semanticscholar   +1 more source

Epidemiological Survey and Genomic Insights Into Ostreid Herpesvirus 1 Transmission in the Blood Clam Anadara broughtonii in China (2019–2025)

Animal Research and One Health, EarlyView.
Seven‐year surveillance reveals a cold‐adapted OsHV‐1 lineage in blood clams, with disease onset at 13°C—3–5°C lower than in oysters—and identifies asymptomatic carriers and facility effluent as key transmission routes. ABSTRACT Ostreid herpesvirus 1 (OsHV‐1) poses a major threat to bivalve aquaculture, but its impact on blood clams (Anadara ...
Xiang Zhang, Bowen Huang, Tao Yu, Jingli Wang, Maole Wei, Huigang Kang, Chongming Wang, Changming Bai   +7 more
wiley   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Estudio del lenguaje sexista en la Empresa Puerto Moa

, 2013
Trabajo de DiplomaEn la investigación: Estudio del lenguaje Sexista en la Empresa Puerto Moa, se analizan los antecedentes teóricos sobre el lenguaje sexista. Se caracteriza la Empresa Puerto Moa.
Ortiz Pérez, Isabel Luisa
core   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Model‐informed optimal dose selection of golcadomide in combination with R‐CHOP in patients with previously untreated aggressive B‐cell lymphoma

British Journal of Clinical Pharmacology, EarlyView.
Aims Golcadomide is a potential first‐in‐class oral CELMoD™ agent for the treatment of lymphoma. This study aims to develop model‐informed drug development (MIDD) approaches to support optimal dose selection of golcadomide in combination with immunotherapy rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R‐CHOP) in alignment with ...
Xirong Zheng, Zhiling Yu, Mark Kaplan, Argyrios Gkasiamis, Akshay Sudhindra, Li Zhu, Manisha Lamba, Fan Wu   +7 more
wiley   +1 more source

Stereochemical Studies of the Karlotoxin Class Using NMR and DP4 Chemical Shift Analysis and Insights into their Mechanism of Action (MoA)

Angewandte Chemie, 2015
Following the publication of karlotoxin 2 (KmTx2, 1), the harmful algal bloom dinoflagellate Karlodinium sp. was collected from oceans and bays throughout the world and scrutinized to identify additional biologically active complex polyketides.
Amanda L. Waters, J. Oh, A. Place, M. Hamann   +3 more
semanticscholar   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino, Jean‐Marie Mouillon, Gisela Nadal‐Rey, Carina L. Gargalo, Ulrich Krühne, Krist V. Gernaey, Mads O. Albæk   +6 more
wiley   +1 more source

Die Moa

, 1916
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources