Results 91 to 100 of about 200,952 (195)

Unveiling the Relationship Between Cultural Values and Public (Dis)Value: The Mediation Role of Corruption Perception and Citizen Trust

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT In recent years, much emphasis has been placed in the literature on understanding the dynamics by which public value is created and destroyed, by analyzing how cultural values contribute to these dynamics. This paper aims to explore the mediation role of corruption perception and citizen trust in explaining the relationship between cultural ...
Paolo Esposito, Emanuele Doronzo, Massimiliano Tufo, Vincenzo Riso   +3 more
wiley   +1 more source

Analytical and Pharmacological Characterization of 1‐(Furan‐2‐Carbonyl)‐LSD (1F‐LSD) and Comparison With 1‐(Thiophene‐2‐Carbonyl)‐LSD (1T‐LSD)

Drug Testing and Analysis, EarlyView.
The novel lysergamide 1‐(furan‐2‐carbonyl)‐LSD (1F‐LSD) was analytically characterized. 1F‐LSD showed LSD‐like activity in vivo similar to 1‐(thiophene‐2‐carbonyl)‐LSD (1T‐LSD) used for comparison. Administration studies in mice and LC–MS analysis revealed that 1F‐LSD served as a prodrug.
Simon D. Brandt, Pierce V. Kavanagh, Sarah Gare, Simon P. Elliott, Alexander Stratford, Adam L. Halberstadt   +5 more
wiley   +1 more source

Dilated cardiomyopathy evaluation with Imagenomics: combining multimodal cardiovascular imaging and genetics

ESC Heart Failure, EarlyView.
Systematic approach to dilated cardiomyopathy diagnosis. Dilated cardiomyopathy is a clinical diagnosis characterized by the presence of left ventricular dilatation and systolic disfunction unexplained by abnormal loading conditions or coronary artery disease.
Kristian Galanti, Ghaith Sharaf Dabbagh, Fabrizio Ricci, Sabina Gallina, Roberta Giansante, Ron Jacob, Edmond Obeng‐Gyimah, Leslie T. Cooper Jr, Sanjay K. Prasad, David H. Birnie, Andrew P. Landstrom, Selma F. Mohammed, Saidi Mohiddin, Mohammed Y. Khanji, Anwar A. Chahal   +14 more
wiley   +1 more source

Heart failure and obesity: Translational approaches and therapeutic perspectives. A scientific statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
Abstract Obesity and heart failure (HF) represent two growing pandemics. In the general population, obesity affects one in eight adults and is linked with an increased risk for HF. Obesity is even more common in patients with HF, where it complicates the diagnosis of HF and is linked with worse symptoms and impaired exercise capacity. Over the past few
Gianluigi Savarese, Gabriele G. Schiattarella, Felix Lindberg, Markus S. Anker, Antoni Bayes‐Genis, Magnus Bäck, Frieder Braunschweig, Chiara Bucciarelli‐Ducci, Javed Butler, Antonio Cannata, Federico Capone, Ovidiu Chioncel, Emilia D'Elia, Arantxa González, Gerasimos Filippatos, Nicolas Girerd, Jean‐Sébastien Hulot, Carolyn S.P. Lam, Lars H. Lund, Christoph Maack, Brenda Moura, Mark C. Petrie, Massimo Piepoli, Abdullah Shehab, Mehmet B. Yilmaz, Peter Seferovic, Carlo G. Tocchetti, Giuseppe M.C. Rosano, Marco Metra   +28 more
wiley   +1 more source

Exploring the Potential of Liposomal Delivery of Naringenin and Berberine for Browning Adipose Tissue and Obesity Management

European Journal of Lipid Science and Technology, EarlyView.
Biocompatible and biodegradable liposomes were developed to encapsulate naringenin (N) and berberine (B), enhancing their stability and bioavailability. Their effects on thermogenesis and browning in 3T3‐L1 preadipocyte cells compared to their free forms were investigated.
Elif Didem Örs Demet, Kübra Uçar Baş, Aslıhan Alpaslan, Dilem Tuğal Aslan, Tuba Reçber, Tuğba Gülsün, Mustafa Çelebier, Zeynep Göktaş   +7 more
wiley   +1 more source

Lithocarpus polystachyus Rehd. leaves aqueous extract inhibits learning and memory impairment in Alzheimer's disease rats: Involvement of the SIRT6/NLRP3 signaling pathway

Ibrain, EarlyView.
The findings of this study demonstrate that STAE effectively counteracts the learning and memory impairment induced by Aβ25‐35 in rats. This effect is attributed, at least in part, to the regulation of the SIRT6/NLRP3 signaling pathway, which inhibits neuroinflammation and oxidative stress.
Wendan Wu, You Yan, Tingting Yi, Yu Wei, Jianmei Gao, Qihai Gong   +5 more
wiley   +1 more source

Effects of SADS‐CoV accessory proteins NS3a, NS7a, and NS7b on viral pathogenicity: A multi‐omics investigation

iMetaOmics, EarlyView.
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan, Xiaoli Zhang, Ling Zhou, Xiaoya Zhao, Qianniu Li, Tian Lan, Jun Fu, Jingyun Ma   +7 more
wiley   +1 more source

Spatio‐temporal characteristics of the gastrointestinal resistome in a cow‐to‐calf model and its environmental dissemination in a dairy production system

iMeta, EarlyView.
This study revealed spatio‐temporal characteristics of gastrointestinal resistome in a cow‐to‐calf model and the pattern of their spread to the environment and offspring in the dairy production system. The gastrointestinal tract of dairy cows is a natural reservoir of resistomes and distinguished by gut sites and regions.
Shuai Liu, Yimin Zhuang, Tianyu Chen, Duo Gao, Jianxin Xiao, Jinfeng Wang, Jinghui Li, Xinjie Zhao, Rong Peng, Wenli Guo, Jialin Wei, Mo Sha, Jingjun Wang, Jiaying Ma, Mei Ma, Mengmeng Li, Wei Wang, Ya‐Jing Wang, Shengli Li, Zhijun Cao   +19 more
wiley   +1 more source

Reimagining pharmacy processes for expanding hospital at‐home care in Singapore: A qualitative study

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
Abstract Introduction Mobile Inpatient Care at Home (MIC@Home) is an alternative acute care model that offers care within patients' homes instead of in traditional hospital settings. This qualitative study seeks to investigate existing perspectives on MIC@Home and the challenges associated specifically with its provision of pharmacy services, and ...
Brian Lee, Hazel Syn, Valerie Ng, Yi Feng Lai   +3 more
wiley   +1 more source

Optimized Long‐TE 1H sLASER MR Spectroscopic Imaging at 3T for Separate Quantification of Glutamate and Glutamine in Glioma

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Glutamate and glutamine are critical metabolites in gliomas, each serving distinct roles in tumor biology. Separate quantification of these metabolites using in vivo MR spectroscopy (MRS) at clinical field strengths (≤ 3T) is hindered by their molecular similarity, resulting in overlapping, hence indistinguishable, spectral peaks ...
Seyma Alcicek, Michael W. Ronellenfitsch, Joachim P. Steinbach, Andrei Manzhurtsev, Dennis C. Thomas, Katharina J. Weber, Vincent Prinz, Marie‐Thérèse Forster, Elke Hattingen, Ulrich Pilatus, Katharina J. Wenger   +10 more
wiley   +1 more source