Results 51 to 60 of about 200,952 (195)

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Routing in Mobile Ad hoc Networks [PDF]

, 2011
A mobile ad hoc network (MANET), sometimes called a mobile mesh network, is a selfconfiguring network of mobile devices connected by wireless links. In other words, a MANET is a collection of communication nodes that wish to communicate with each other, but has no fixed infrastructure and no predetermined topology of wireless links.
openaire   +3 more sources

TCP Performance in Mobile Ad hoc Networks

Network Protocols and Algorithms, 2013
In this paper, we present a survey of TCP (Transmission Control Protocol) protocol for better performance in the MANET (Mobile Ad Hoc Network). After a short presentation of the main features of TCP, we give the most important problems from which TCP suffer in MANET.
Hamrioui, Sofiane, Lloret, Jaime, Lorenz, Pascal, Lalam, Mustapha   +3 more
openaire   +4 more sources

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Secure Routing in Mobile Ad hoc Network

Sukkur IBA Journal of Computing and Mathematical Sciences, 2018
Abstract— MANET is a wireless Mobile ad-hoc network which includes mobile nodes. In MANET mobile refers to the movable nodes which can change their location frequently. MANET is a network which has no central infrastructure; it is a self-managing and self-configuring network. In MANET devices can be heterogeneous like laptops, mobiles, PDAs etc. Due to
Irsa Naz, Sumbal Abbas, Sabrina Bashir
openaire   +6 more sources

Spontaneous Ad Hoc Mobile Cloud Computing Network [PDF]

The Scientific World Journal, 2014
Cloud computing helps users and companies to share computing resources instead of having local servers or personal devices to handle the applications. Smart devices are becoming one of the main information processing devices. Their computing features are reaching levels that let them create a mobile cloud computing network.
Lacuesta, Raquel, Lloret, Jaime, Sendra, Sandra, Peñalver Herrero, Mª Lourdes   +3 more
openaire   +5 more sources

On Energy Efficient Hierarchical Cross-Layer Design: Joint Power Control and Routing for Ad Hoc Networks

, 2007
In this paper, a hierarchical cross-layer design approach is proposed to increase energy efficiency in ad hoc networks through joint adaptation of nodes' transmitting powers and route selection.
Comaniciu, Cristina, Poor, H. Vincent
core   +3 more sources

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

Advanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu, Yuanyuan Zhu, Guangjue Tang, Ming Shan, Puwen Tan, Ying Yi, Xiyuan Zhang, Man Liu, Xinyu Li, Le Wu, Jia Chen, Hailong Zheng, Yan Huang, Zhuan Li, Xiaobo Li, Dong Wang   +15 more
wiley   +1 more source

A Contribution to Secure the Routing Protocol "Greedy Perimeter Stateless Routing" Using a Symmetric Signature-Based AES and MD5 Hash

, 2011
This work presents a contribution to secure the routing protocol GPSR (Greedy Perimeter Stateless Routing) for vehicular ad hoc networks, we examine the possible attacks against GPSR and security solutions proposed by different research teams working on ...
Erritali, Mohammed, Ouahidi, Bouabid El, Reda, Oussama Mohamed   +2 more
core   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source