Results 71 to 80 of about 14,634,052 (312)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Scheme of mobile informatization in electric power enterprise
Dianxin kexue, 2017 The electric power enterprises' mobile information development trend was analyzed,an enterprises' mobile informatization scheme based on enterprise “mobile platform and mobile applications”was put forward,including the overall technical route and the ...
Hualu ZHANG +3 more
doaj +2 more sources
GraphQL or REST for Mobile Applications?
, 2022 Currently, GraphQL has emerged as a query language for developing web APIs that propose to improve several data access problems of RESTful APIs. The present paper aims to study the effects on software quality of APIs developed with REST and GraphQL architectures consumed from mobile applications.
Antonio Quiña-Mera +4 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Development of an educational mobile application for patients submitted to orthognathic surgery
Revista Latino-Americana de Enfermagem, 2019 Objective: to develop, evaluate and correlate the acceptability of an educational mobile application to patients submitted to orthognathic surgery. Method: methodological study based on systematic instructional design with contents aimed at patient ...
C. Sousa, R. Turrini
semanticscholar +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Research on the HTML5 Application Runtime Environment for Mobile Terminal
Dianxin kexue, 2013 A new generation of Web HTML5 standard has become a general technical standard for mobile internet application platform in the future，and mobile Web application based on HTML5 is becoming a new form of application.
Gang Lu +3 more
doaj +2 more sources