Results 71 to 80 of about 460,385 (314)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Monetizing mobile applications

open access: yes, 2013
Although the mobile applications are everywhere and even if you have a brilliant idea, the monetization of a mobile application is not an easy task. On the other side, there are examples of companies and individuals which make an enormous amount of money on their free apps. How is that possible? Well, obviously, they have chosen the successful business
Tomaš, Boris   +2 more
openaire   +2 more sources

Research on the HTML5 Application Runtime Environment for Mobile Terminal

open access: yesDianxin kexue, 2013
A new generation of Web HTML5 standard has become a general technical standard for mobile internet application platform in the future,and mobile Web application based on HTML5 is becoming a new form of application.
Gang Lu   +3 more
doaj   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Application Mobility

open access: yes, 2015
Mobility has become an omnipresent part of our modern IT society. Alongside the general taxonomy of mobile users, terminals, sessions, and services, there are also more specialized forms of mobility. Context-Awareness Supported Application Mobility (CASAM) or “Application Mobility” is one such form that is explored in this chapter.
Johansson, Dan, Wiberg, Mikael
openaire   +2 more sources

Mobile Applications for Active Aging [PDF]

open access: yes, 2018
Many countries, including several European states are aging. This demographic change opens a variety of opportunities for innovation in products and services tailored to the needs of an aging population. This paper focus on how ICT-based mobile application can be used to potentiate active aging. The role that mobile computing can play in the support of
Cláudia Ferreira   +2 more
openaire   +3 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

A Collaborative Multimedia Application for a Mobile Environment [PDF]

open access: yes, 1995
With recent advances in portable computers and wireless networks, it is now feasible to provide sophisticated IT support for a range of mobile workers in areas such as the police, ambulance services and the utilities industries.
Friday, Adrian   +3 more
core  

A Comparison of a Smartphone App with Other GPS Tracking Type Devices Employed in Football [PDF]

open access: yesExercise Medicine, 2019
OBJECTIVES The purpose of this study was to evaluate the use of a smartphone application in comparison against current GPS tracking type devices that are used to track players during football training and match play.
Peter Tierney, Neil Clarke
doaj   +1 more source

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