Results 91 to 100 of about 272,523 (346)

Bacteremia caused by an Acinetobacter junii strain harboring class 1 integron and diverse DNA mobile elements [PDF]

, 2014
INTRODUCTION: Infections caused by Acinetobacter junii are rarely reported. However, some outbreaks of septicemia in neonates and pediatric oncology patients, as well as meningitis, peritonitis, and ocular infection have been described.
Almuzara, Marisa, Centron, Daniela, Neumann, Gabriela, Pallone, Elida Carmen, Ramirez, Maria Soledad, Traglia, German Matias, Tuduri, Alicia, Vilacoba, Elisabet   +7 more
core   +1 more source

The Gypsy Database (GyDB) of mobile genetic elements [PDF]

Nucleic Acids Research, 2007
In this article, we introduce the Gypsy Database (GyDB) of mobile genetic elements, an in-progress database devoted to the non-redundant analysis and evolutionary-based classification of mobile genetic elements. In this first version, we contemplate eukaryotic Ty3/Gypsy and Retroviridae long terminal repeats (LTR) retroelements.
Ricardo Futami, Carlos Llorens, Andrés Moya, Daniela Bezemer   +3 more
openaire   +3 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Hybrid Iterative Multiuser Detection for Channel Coded Space Division Multiple Access OFDM Systems [PDF]

, 2006
Space division multiple access (SDMA) aided orthogonal frequency division multiplexing (OFDM) systems assisted by efficient multiuser detection (MUD) techniques have recently attracted intensive research interests.
Hanzo, L., Jiang, M., Ng, S. X.
core   +2 more sources

Jumping around the Topic of Mobile Genetic Elements [PDF]

Cell, 1997
Behe Michael J., Darwin's Black Box, 1996, Free Press, New York, 289, $25.00Bell, R.M., Exton, J.H., Prescott, S.M., Handbook of Lipid Research, 1996, Plenum Press, New York, 316, $89.50Birren, B., Lai, E., Nonmammalian Genomic Analysis, A Practical Guide, , 1996, Academic Press, San Diego, California, 353, $39.95Biswas, B.B., Biswas, S., Subcellular ...
Carlos Flores, Bill Engels
openaire   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Crosstalk Between Type VI Secretion System and Mobile Genetic Elements

Frontiers in Molecular Biosciences, 2019
Many bacterial processes require cell-cell contacts. Such are the cases of bacterial conjugation, one of the main horizontal gene transfer mechanisms that physically spreads DNA, and the type VI secretion systems (T6SSs), which deploy antibacterial ...
Arancha Peñil-Celis, M. Pilar Garcillán-Barcia   +1 more
doaj   +1 more source

Pathogenomics insights for understanding Pasteurella multocida adaptation

International Journal of Medical Microbiology, 2020
Pasteurella multocida is an important veterinary pathogen able to infect a wide range of animals in a broad spectrum of diseases. P. multocida is a complex microorganism in relation to its genomic flexibility, host adaptation and pathogenesis ...
Raquel Hurtado, Lenin Maturrano, Vasco Azevedo, Flávia Aburjaile   +3 more
doaj   +1 more source

Likelihood-Based Inference for Discretely Observed Birth-Death-Shift Processes, with Applications to Evolution of Mobile Genetic Elements

, 2014
Continuous-time birth-death-shift (BDS) processes are frequently used in stochastic modeling, with many applications in ecology and epidemiology. In particular, such processes can model evolutionary dynamics of transposable elements - important genetic ...
Biémont, Catlin, Cattamanchi, Crawford, Crawford, Dempster, Doss, Gagneux, Golinelli, Henrici, Huber, Kato-Maeda, Keiding, Lange, McEvoy, Minin, Rosenberg, Schwarz, Tanaka, Van Embden   +19 more
core   +1 more source