Results 51 to 60 of about 410,012 (337)

Identifying Structural Variation in Haploid Microbial Genomes from Short-Read Resequencing Data Using Breseq [PDF]

, 2014
Mutations that alter chromosomal structure play critical roles in evolution and disease, including in the origin of new lifestyles and pathogenic traits in microbes.
Barrick, Jeffrey E., Borges, Jordan J., Colburn, Geoffrey, Deatherage, Daniel E., Knoester, David B., Meyer, Austin G., Reba, Aaron, Strand, Matthew D., Traverse, Charles C.   +8 more
core   +1 more source

Compatibility of Site-Specific Recombination Units between Mobile Genetic Elements

iScience, 2020
Summary: Site-specific recombination (SSR) systems are employed for transfer of mobile genetic elements (MGEs), such as lysogenic phages and integrative conjugative elements (ICEs).
Shota Suzuki, Miki Yoshikawa, Daisuke Imamura, Kimihiro Abe, Patrick Eichenberger, Tsutomu Sato   +5 more
doaj   +1 more source

The ESKAPE mobilome contributes to the spread of antimicrobial resistance and CRISPR-mediated conflict between mobile genetic elements

bioRxiv, 2022
Mobile genetic elements (MGEs) mediate the shuffling of genes among organisms. They contribute to the spread of virulence and antibiotic resistance genes in human pathogens, such as the particularly problematic group of ESKAPE pathogens, including ...
João Botelho, Adrián Cazares, H. Schulenburg   +2 more
semanticscholar   +1 more source

Mobile DNA can drive lineage extinction in prokaryotic populations [PDF]

, 2010
Natural selection ultimately acts on genes and other DNA sequences. Adaptations that are good for the gene can have adverse effects at higher levels of organization, including the individual or the population.
Alizon, Anderson, Arkhipova, Arkhipova, Bartolome, Bergstrom, Bestor, Blot, Boots, Boots, Brookfield, Brookfield, Brookfield, Burt, Capy, Charlesworth, Charlesworth, De Jong, Dieckmann, Dolgin, Doolittle, Dunham, Edwards, Ewald, Frank, Frank, Gandon, Gersani, Griffin, Gyllenberg, Hardin, Hickey, Horvath, Jablonski, Johnson, Kerr, Kokko, Lande, Langley, Lewontin, Lili, Lipsitch, Martin, Matsuda, May, Maynard Smith, Mc Ginty, McCallum, Nunney, Ochman, Okasha, Orgel, Parvinen, Rankin, Rankin, Rankin, Rankin, Rankin, Rankin, Sawyer, Smith, Touchon, Van Valen, Vinogradov, Vinogradov, Vinogradov, Wagner, Wagner, Wagner, Wagner, Wenseleers   +70 more
core   +1 more source

Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes

Nucleic Acids Research, 2022
Prokaryotic Mobile Genetic Elements (MGEs) such as transposons, integrons, phages and plasmids, play important roles in prokaryotic evolution and in the dispersal of cargo functions like antibiotic resistance.
Supriya Khedkar, Georgy Smyshlyaev, Ivica Letunic, Oleksandr M. Maistrenko, Luis Pedro Coelho, Askarbek N. Orakov, Sofia K. Forslund, F. Hildebrand, M. Luetge, T. Schmidt, O. Barabas, P. Bork   +11 more
semanticscholar   +1 more source

Transcriptional profiling of colicin-induced cell death of Escherichia coli MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversity [PDF]

, 2004
We report the transcriptional response of Escherichia coli MG1655 to damage induced by colicins E3 and E9, bacteriocins that kill cells through inactivation of the ribosome and degradation of chromosomal DNA, respectively. Colicin E9 strongly induced the
Hinton, Jay C. D., James, Richard, Kleanthous, Colin, Moore, Geoffrey R., Rolfe, Matthew, Thompson, Arthur, WALKER, DANIEL   +6 more
core   +2 more sources

Interplay between the cell envelope and mobile genetic elements shapes gene flow in populations of the nosocomial pathogen Klebsiella pneumoniae

PLoS Biology, 2021
Mobile genetic elements (MGEs) drive genetic transfers between bacteria using mechanisms that require a physical interaction with the cellular envelope.
Matthieu Haudiquet, A. Buffet, Olaya Rendueles, E. Rocha   +3 more
semanticscholar   +1 more source

Unveiling Mobilizable Multiresistance Clusters in Marine Bacteria

Engineering Proceedings, 2023
The occurrence and spread of antibiotic resistance have become a pressing global health concern. Understanding the genetic elements that facilitate the dissemination of antibiotic resistance genes (ARGs) in marine environments is crucial for effective ...
Adeel Farooq, Asma Rafique
doaj   +1 more source

Anti-phage islands force their target phage to directly mediate island excision and spread. [PDF]

, 2018
Vibrio cholerae, the causative agent of the diarrheal disease cholera, is antagonized by the lytic phage ICP1 in the aquatic environment and in human hosts. Mobile genetic elements called PLEs (phage-inducible chromosomal island-like elements) protect V.
McKitterick, Amelia C, Seed, Kimberley D
core   +1 more source

Interactions between mobile genetic elements: An anti-phage gene in an integrative and conjugative element protects host cells from predation by a temperate bacteriophage

PLoS Genetics, 2022
Most bacterial genomes contain horizontally acquired and transmissible mobile genetic elements, including temperate bacteriophages and integrative and conjugative elements.
Christopher M. Johnson, M. Harden, A. Grossman   +2 more
semanticscholar   +1 more source