Results 61 to 70 of about 522,356 (262)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Mobile health clinic model in the COVID-19 pandemic: lessons learned and opportunities for policy changes and innovation

International Journal for Equity in Health, 2020
Background Mobile Clinics represent an untapped resource for our healthcare system. The COVID-19 pandemic has exacerbated its limitations. Mobile health clinic programs in the US already play important, albeit under-appreciated roles in the healthcare ...
Sharon Attipoe-Dorcoo, Rigoberto Delgado, Aditi Gupta, Jennifer Bennet, Nancy E. Oriol, Sachin H. Jain   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A machine learning-based approach for constructing remote photoplethysmogram signals from video cameras

Communications Medicine
Background Advancements in health monitoring technologies are increasingly relying on capturing heart signals from video, a method known as remote photoplethysmography (rPPG). This study aims to enhance the accuracy of rPPG signals using a novel computer
Rodrigo Castellano Ontiveros, Mohamed Elgendi, Carlo Menon   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Fully textile passive wireless sensing for human movement monitoring with multiple sensors

Frontiers in Bioengineering and Biotechnology
Movement monitoring with wearable technologies is becoming increasingly popular in different fields of application (clinical, sports, entertainment). Particularly, textile-based wearables for movement monitoring are attractive as they follow the body ...
Valeria Galli, Chakaveh Ahmadizadeh, Carlo Menon   +2 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Concomitant carotid-carotid-axillary bypass with zone 0 branched endograft and transcatheter aortic valve-in-valve replacement via retroperitoneal accessCentral Message

JTCVS Techniques, 2023
Kareem Bedeir, MD, MSc, Chad McRee, MD, FACC, William E. Johnson, MD   +2 more
doaj   +1 more source

Mobile health [PDF]

Electronic Markets, 2013
Doug Vogel, Dennis Viehland, Nilmini Wickramasinghe, Joseph M. Mula   +3 more
openaire   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source