Results 71 to 80 of about 13,656,447 (254)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Mobile health clinic model in the COVID-19 pandemic: lessons learned and opportunities for policy changes and innovation

open access: yesInternational Journal for Equity in Health, 2020
Background Mobile Clinics represent an untapped resource for our healthcare system. The COVID-19 pandemic has exacerbated its limitations. Mobile health clinic programs in the US already play important, albeit under-appreciated roles in the healthcare ...
Sharon Attipoe-Dorcoo   +5 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Proposal name: City of Mobile flood risk management & ecosystem restoration study

open access: yes, 2023
Report to Congress for Future Water Resources Development (WRRDA 7001) Submission Package Proposal Name: City of Mobile Flood Risk Management & Ecosystem Restoration Study Submission Date: 08/29/2022 Proposal ID Number: 2ee57f30-49fc-4220-911f ...
Mobile (Ala.);
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A machine learning-based approach for constructing remote photoplethysmogram signals from video cameras

open access: yesCommunications Medicine
Background Advancements in health monitoring technologies are increasingly relying on capturing heart signals from video, a method known as remote photoplethysmography (rPPG). This study aims to enhance the accuracy of rPPG signals using a novel computer
Rodrigo Castellano Ontiveros   +2 more
doaj   +1 more source

Crowding at Lake Chad : an integrated approach to demographic and health surveillance of mobile pastoralists and their animals [PDF]

open access: yes, 2015
Despite substantial contribution to the economies of their countries, mobile pastoralists are marginalised in many aspects of their daily lives. Mobility complicates their access to schooling or health and veterinary services.
Jean-Richard, Vreni
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Fully textile passive wireless sensing for human movement monitoring with multiple sensors

open access: yesFrontiers in Bioengineering and Biotechnology
Movement monitoring with wearable technologies is becoming increasingly popular in different fields of application (clinical, sports, entertainment). Particularly, textile-based wearables for movement monitoring are attractive as they follow the body ...
Valeria Galli   +2 more
doaj   +1 more source

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