Results 81 to 90 of about 1,728,446 (297)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Fully textile passive wireless sensing for human movement monitoring with multiple sensors

open access: yesFrontiers in Bioengineering and Biotechnology
Movement monitoring with wearable technologies is becoming increasingly popular in different fields of application (clinical, sports, entertainment). Particularly, textile-based wearables for movement monitoring are attractive as they follow the body ...
Valeria Galli   +2 more
doaj   +1 more source

Mobile health clinic model in the COVID-19 pandemic: lessons learned and opportunities for policy changes and innovation

open access: yesInternational Journal for Equity in Health, 2020
Background Mobile Clinics represent an untapped resource for our healthcare system. The COVID-19 pandemic has exacerbated its limitations. Mobile health clinic programs in the US already play important, albeit under-appreciated roles in the healthcare ...
Sharon Attipoe-Dorcoo   +5 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

A machine learning-based approach for constructing remote photoplethysmogram signals from video cameras

open access: yesCommunications Medicine
Background Advancements in health monitoring technologies are increasingly relying on capturing heart signals from video, a method known as remote photoplethysmography (rPPG). This study aims to enhance the accuracy of rPPG signals using a novel computer
Rodrigo Castellano Ontiveros   +2 more
doaj   +1 more source

Health Phones: A Potential Game Changer in Health Information Management [PDF]

open access: yes, 2011
Health education has to be one of the most effective ways to reduce morbidity and mortality in developing countries. We need to deliver vital messages and information to people at the lower quarter of the society to use changing behaviour and practices ...
Skaria, GM
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Ubiquitous computing and knowledge management [PDF]

open access: yes, 2006
MOBIlearn is a large European research project to develop a mobile learning system to facilitate formal, non formal and informal learning. The project has two primary objectives: • Develop a methodology for creating mobile learning scenarios and ...
Crowther, P.
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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