Results 51 to 60 of about 536,548 (315)

Modular Mobile Crisis Management Support Systems – Implementation Prospects Based on the Analysis of the Beirut Explosion (2020) [PDF]

open access: yesSafety & Fire Technology
Purpose: The purpose of this article is a comprehensive analysis of implementation options of modular mobile crisis management support systems (MMCMSS) in the context of contemporary CBRNE hazards, including in particular incidents involving ammonium ...
Norbert Tuśnio
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Investigations for a Trajectory Variation to Improve the Energy Conversion for a Four-Stroke Free-Piston Engine

open access: yesApplied Sciences, 2021
Internal combustion engines with a crankshaft have been successfully developed for many years. They are lacking in the fact that the piston trajectory, i.e., position as a function of time, is limited by the crankshaft motion law.
Robin Tempelhagen   +5 more
doaj   +1 more source

A Toolset for Mobile Systems Testing [PDF]

open access: yes, 2017
Validation of mobile applications needs taking account of context (such network topology) and interactions between mobile nodes. Scenario-based approaches are well-suited to describe the behavior and interactions to observe in distributed systems. The difficulty to control accurately the execution context of such applications has led us to use passive ...
André, Pierre   +2 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Don't kill my ads! balancing privacy in an ad-supported mobile application market [PDF]

open access: yes, 2012
Application markets have revolutionized the software download model of mobile phones: third-party application developers offer software on the market that users can effortlessly install on their phones. This great step forward, however, also imposes some
Leontiadis, Ilias   +7 more
core   +1 more source

Achieving NOx Emissions with Zero-Impact on Air Quality from Diesel Light-Duty Commercial Vehicles

open access: yesEnergies
Many cities are still struggling to comply with current air quality regulations. Road transport is usually a significant source of NOx emissions, especially in urban areas.
Theodoros Kossioris   +4 more
doaj   +1 more source

Spherical Coverage Characterization of 5G Millimeter Wave User Equipment With 3GPP Specifications

open access: yesIEEE Access, 2019
Millimeter-wave (mmWave) frequency bands are promising candidate spectrum for the fifth-generation (5G) mobile communication system, but it requires high directional antenna systems to be applied to the base station and the user equipment (UE) for ...
Kun Zhao   +6 more
doaj   +1 more source

Optimization-Based Tuning of a Hybrid UKF State Estimator with Tire Model Adaption for an All Wheel Drive Electric Vehicle

open access: yesEnergies, 2021
Novel drivetrain concepts such as electric direct drives can improve vehicle dynamic control due to faster, more accurate, and more flexible generation of wheel individual propulsion and braking torques.
Hannes Heidfeld, Martin Schünemann
doaj   +1 more source

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