Results 61 to 70 of about 536,548 (315)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Control strategy for a hydrogen combustion engine with lean and stoichiometric combustion system
Hydrogen presents a promising opportunity for the reduction of CO2 emissions in combustion processes. Due to its wide ignition limits, operation in lean mode is possible, which significantly reduces NO x emissions. However, this lean operation also leads
Katrin Himmelseher +11 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
SATIN: a component model for mobile self-organisation [PDF]
We have recently witnessed a growing interest in self organising systems, both in research and in practice. These systems re-organise in response to new or changing conditions in the environment.
Zachariadis, S. +5 more
core +1 more source
Resource Allocation in V2X Networks: From Classical Optimization to Machine Learning-Based Solutions
As one of the promising intelligent transportation frameworks, vehicular platooning has the potential to bring about sustainable and efficient mobility solutions. One of the challenges in the development of platooning is maintaining the string stability,
Mohammad Parvini +2 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Virtual Plug-In Hybrid Concept Development and Optimization under Real-World Boundary Conditions
The automotive industry faces development challenges due to emerging technologies, regulatory demands, societal trends, and evolving customer mobility needs.
Jannik Kexel +5 more
doaj +1 more source
Study on sinusoidal estimation deviation of electrostatic actuated MEMS mirror torsion angle
Electrostatic MEMS micromirrors usually work in resonant state to obtain large amplitude of torsion angle. The real-time prediction of MEMS micromirror torsion angle is calculated according to the measured resonant amplitude and phase under the ...
LI Jingang +5 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

