Results 91 to 100 of about 4,118,168 (395)
Exploiting code mobility for dynamic binary obfuscation [PDF]
, 2011 Software protection aims at protecting the integrity of software applications deployed on un-trusted hosts and being subject to illegal analysis. Within an un-trusted environment a possibly malicious user has complete access to system resources and tools
Barberis, Davide +4 more
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Mobility, mixing and neighbourhood change: a British perspective [PDF]
, 2012 The articles in this symposium highlight three important areas of inquiry related to residential mobility—what constitutes mobility, the processes of mobility, and the effects of mobility on different groups and locations.
Kearns, A.
core
, 2018 Transport of an inertial particle advected by a two-dimensional steady laminar flow is numerically investigated in the presences of a constant force and a periodic potential.
Ai, Bao-quan +3 more
core +1 more source
Association of Specific Leg Muscle Strength and Motor Features in Parkinson’s Disease
Parkinson's DiseaseBackground. Postural instability and gait difficulties (PIGD) are a significant cause of falls, mobility loss, and lower quality of life in Parkinson’s disease (PD).
Chatkaew Pongmala +6 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Spacesuit mobility knee joints [PDF]
, 1979 Pressure suit mobility joints are for use in interconnecting adjacent segments of an hermetically sealed spacesuit in which low torques, low leakage and a high degree of reliability are required.
Vykukal, H. C.
core +1 more source
A novel middleware for the mobility management over the Internet [PDF]
, 2008 The features of mobility, which enormously impact on how communication is evolving into the future, represent a particular challenge in today’s wireless networking research. After an identification and evaluation of the gap between the discontinuities of
Diaz, Michel +3 more
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Genetics and Economic Mobility [PDF]
, 2008 Presents a literature review on the link between genetic traits, such as cognitive skills, health, mental health, personality, and appearance, and academic and economic success.
Jessica Kronstadt
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