Results 51 to 60 of about 3,094,057 (286)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Particle Dampers for Vibration Reduction Designed for a Motorcycle Handlebar

open access: yesShock and Vibration
Health problems caused by excessive handle–arm vibrations (HAV) are very frequent in professionals working with machines that generate cyclic loads, like some hand tools (chainsaws, impulse tools and hammer drills, e.g.) and vehicles (like tractors and ...
Felipe Klein Fiorentin   +4 more
doaj   +1 more source

Coordinated formation control for intelligent and connected vehicles in multiple traffic scenarios

open access: yesIET Intelligent Transport Systems, 2021
In this paper, a unified multi‐vehicle formation control framework for intelligent and connected vehicles (ICVs) that can apply to multiple traffic scenarios is proposed.
Qing Xu   +5 more
doaj   +1 more source

Accurate Remaining Available Energy Estimation of LiFePO4 Battery in Dynamic Frequency Regulation for EVs with Thermal-Electric-Hysteresis Model

open access: yesEnergies, 2023
Renewable energy power generation systems such as photovoltaic and wind power have characteristics of intermittency and volatility, which can cause disturbances to the grid frequency.
Zhihang Zhang   +4 more
doaj   +1 more source

Hardware Design of 3-Axis Motion Platform with Load Compensation Mechanism [PDF]

open access: yes한국정밀공학회지, 2020
The motion platform supports the trainee in experiencing a sense of reality in virtual space by performing a motion on the available degrees of freedom for a motion that mimics a specific motion in connection with a virtual reality content or a simulator.
Jeong Woo Park   +4 more
doaj   +1 more source

Universal Predictability of Mobility Patterns in Cities

open access: yes, 2014
Despite the long history of modelling human mobility, we continue to lack a highly accurate approach with low data requirements for predicting mobility patterns in cities.
Di, Zengru   +4 more
core   +1 more source

Stochastic Dominance in Mobility Analysis [PDF]

open access: yes, 2002
This paper introduces a technique for mobility dominance and compares the degree of earnings mobility of men in the USA from 1970 to 1995.
Fields, Gary S   +2 more
core   +2 more sources

MOBILE COMMUNICATIONS, MOBILE LANGUAGE

open access: yesInformation and Telecommunication Sciences, 2013
The present paper addresses essential discourse elements of the English language of science in light of the so-called Anglo-American intellectual style. Emphasised here are: various linguistic devices of compression (writing succinctly, avoidingverbosity and negation etc.), keeping subject and verb close together, and common revision patterns.
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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