Results 11 to 20 of about 3,131 (121)

OpenSim Moco: Musculoskeletal optimal control [PDF]

open access: yesPLOS Computational Biology, 2019
Musculoskeletal simulations are used in many different applications, ranging from the design of wearable robots that interact with humans to the analysis of patients with impaired movement. Here, we introduce OpenSim Moco, a software toolkit for optimizing the motion and control of musculoskeletal models built in the OpenSim modeling and simulation ...
Christopher L. Dembia   +4 more
openaire   +8 more sources

The structure of the Moco carrier protein fromRippkaea orientalis [PDF]

open access: yesActa Crystallographica Section F Structural Biology Communications, 2020
The molybdenum cofactor (Moco) is the prosthetic group of all molybdenum-dependent enzymes except for nitrogenase. The multistep biosynthesis pathway of Moco and its function in molybdenum-dependent enzymes are already well understood. The mechanisms of Moco transfer, storage and insertion, on the other hand, are not.
Joern Krausze   +3 more
openaire   +6 more sources

Identification and characterisation of the Volvox carteri Moco carrier protein [PDF]

open access: yesBioscience Reports, 2020
Abstract The molybdenum cofactor (Moco) is a redox active prosthetic group found in the active site of Moco-dependent enzymes (Mo-enzymes). As Moco and its intermediates are highly sensitive towards oxidative damage, these are believed to be permanently protein bound during synthesis and upon maturation. As a major component of the plant
Thomas W. Hercher   +4 more
openaire   +6 more sources

Beyond Moco Biosynthesis―Moonlighting Roles of MoaE and MOCS2

open access: yesMolecules, 2022
Molybdenum cofactor (Moco) biosynthesis requires iron, copper, and ATP. The Moco-containing enzyme sulfite oxidase catalyzes terminal oxidation in oxidative cysteine catabolism, and another Moco-containing enzyme, xanthine dehydrogenase, functions in purine catabolism.
Suganuma, Tamaki, Tamaki Suganuma
openaire   +4 more sources

Moco: A Learnable Meta Optimizer for Combinatorial Optimization

open access: yes
Relevant combinatorial optimization problems (COPs) are often NP-hard. While they have been tackled mainly via handcrafted heuristics in the past, advances in neural networks have motivated the development of general methods to learn heuristics from data.
Tim Dernedde   +4 more
openaire   +4 more sources

Learning from the worm: the effectiveness of protein-bound Moco to treat Moco deficiency [PDF]

open access: yesGenes & Development, 2021
Molybdenum cofactor (Moco) is synthesized endogenously in humans and is essential for human development. Supplementation of Moco or its precursors has been explored as a therapy to treat Moco-deficient patients but with significant limitations. By using the nematode C. elegans as a model, Warnhoff and colleagues (pp.
Sewell, Aileen K., Han, Min
openaire   +2 more sources

CF Patient Respiratory Dynamics (MoCo-MSLR: left, Extreme-MRI:right) (supplemental video 6)

open access: yes, 2022
CF Patient with complex respiratory dynamics (targeted temporal resolution: 515 ms) . MoCo-MSLR CINE is left, Extreme MRI CINE is right. Unlike the healthy volunteer case, significant differences in both image quality seen. Subtle differences in dynamics
Zachary Miller (12393946)
core   +1 more source

Paired MoCo-MSLR Reconstruction and Associated Motion Field (supplemental video 10)

open access: yes, 2022
 Paired MoCo-MSLR Reconstruction and Associated Motion Field.
Zachary Miller (12393946)
core   +1 more source

Co3O4/MoCo/Layered Double Hydroxide Nanosheets for Asymmetric Supercapacitor

open access: yes, 2022
Recent research studies have focused on energy storage systems such as supercapacitors with high power density, good operational safety, and durable cycling life.
Ali A. Ensafi (2002663)   +2 more
core   +2 more sources

Free Breathing Placental Imaging (MoCo-MSLR: left, Extreme-MRI: right)

open access: yes, 2022
 Supplemental Video 5.9: Healthy Third Trimester Pregnant Patient Uterine Reconstructions. MoCo-MSLR is left, Extreme MRI is right. Respiratory dynamics are similar with a contraction observed in both reconstructions from 3-5. There is significantly less
Zachary Miller (12393946)
core   +1 more source

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