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The role of urinary pteridines as disease biomarkers
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Casey Burton, Yinfa Ma
exaly +4 more sources
A series of new amino acid-tetrahydropterin-conjugates has been synthesized starting from N 2-isobutyryl-6,7- dimethyl-5,6,7,8-tetrahydropterin (7). The amino acids have been attached in form of their esters (10 - 16) via a succinyl spacer to the N-5 ...
Lockart Ronan John, Pfleiderer Wolfgang
doaj +4 more sources
Biosynthesis of Pteridines in Insects: A Review [PDF]
Pteridines are important cofactors for many biological functions of all living organisms, and they were first discovered as pigments of insects, mainly in butterfly wings and the eye and body colors of insects. Most of the information on their structures
Juan Ferré
doaj +3 more sources
A simple direct method for the synthesis of lumazine-6,7-diamines (9, 25-27) from uracil-5,6-diamines (10-13) and methyl cyanoformimidate (24) was found.
Abou-Hadeed Khaled, Pfleiderer Wolfgang
doaj +4 more sources
Data on urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes [PDF]
Presented here are the supplemental data of the research article “Urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes” [1]. These data provide the first information on variables that affect urinary levels of pteridines
Mikio Marumo +2 more
doaj +2 more sources
Native metabolomics identifies pteridines as CutA ligands and modulators of copper binding [PDF]
CutA, a conserved protein across all domains of life, has been suggested to be involved in copper tolerance in bacteria, though recent studies have questioned this association, leaving its biological role unknown. To clarify its function, we studied cutA
Tilman Schramm +2 more
exaly +3 more sources
Treatment of L-biopterin (I) with N,N-dimethyformamide dimethyl- (or diethyl)acetal and then with acetic anhydride in pyridine gave 1',2'-di-O-acetyl-N'-(N,N-dimethylaminomethylene)-L-biopterin (4), which was converted by the Mitsunobu reaction into 3 ...
Hanaya Tadashi +5 more
doaj +3 more sources
A series of new 6-substituted 2,4-diaminopteridines (3-23) and pterins (26-43) have been synthesized by nucleophilic displacement reactions at the side chain of 6-bromomethyl-2,4-diaminopteridine (2) and 6- bromomethylpterin (25) using various types of 0-
Traub Hermann, Pfleiderer Wolfgang
doaj +2 more sources
Urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes
Background and aims: We have recently proposed urinary pteridine level as a useful biomarker of oxidative stress in a general population. However, the significance of urinary pteridines in patients with diabetes is unknown.
Mikio Marumo +2 more
doaj +1 more source
Flesh flies (Diptera: Sarcophagidae) are regarded as significant in medical and veterinary entomology, and their development models can be utilized as considerable markers to ascertain the minimum postmortem interval (PMImin).
Fernand Jocelin Ngando +9 more
doaj +1 more source

