Results 21 to 30 of about 6,178 (219)

Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies

open access: yesPharmaceuticals, 2023
Structural-based drug design and solvent-free synthesis were combined to obtain three novel series of 5-arylethylidene-aminopyrimidine-2,4-diones (4, 5a–c, 6a,b), 5-arylethylidene-amino-2-thiopyrimidine-4-ones (7,8), and 6-arylpteridines (9,10) as dual ...
Samar El-Kalyoubi   +4 more
doaj   +1 more source

Homology Cloning of GTP-cydohydrolase I from Fungi and Plants by Reverse-transcription PCR Using a General Set of Degenerate Primers

open access: yesPteridines, 1995
Unconjugated pteridines are present in fungi, algae and plants. However, the functions of pteridines in these organisms are not thoroughly investigated. The biosynthesis follows the same steps as were shown for animals and eubacteria.
Maier Josef   +2 more
doaj   +1 more source

Control Strategies in Guanine Biocrystallization

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Biological guanine crystals produce spectacular photonic phenomena in animals and hold great promise as new, sustainable optical materials. We review how organisms precisely control the structure, morphologies, and resulting optical properties of these crystals using a set of ingenious ‘design’ strategies, including control of pH, template‐directed ...
Shashanka S. Indri   +2 more
wiley   +2 more sources

Influence of Neopterin on Ciliary Beat Frequency of Human Nasal Epithelial Cells in vitro

open access: yesPteridines, 2008
Acute infectious diseases of the respiratory tract are regularly associated with increased concentrations of neopterin in serum and/or urine. Most likely, the pteridine compound is not only a marker of an activated cellular immune system but may exert ...
Neher Andreas   +5 more
doaj   +1 more source

Exploring the scope of DBU-promoted amidations of 7-carboxymethyl-pterin [PDF]

open access: yes, 2020
Pteridines are an important heterocycle often used in the development of pharmaceutically relevant compounds, and in the field of supramolecular chemistry.
Bockman, Anna
core   +1 more source

Dilute-and-Shoot-Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry for Pteridine Profiling in Human Urine and Its Association with Different Pathologies

open access: yesChemosensors, 2023
Pteridines are a group of compounds synthesised by many living organisms that are involved in the metabolism of many cofactors and vitamins. Their concentration in biological fluids may be altered by various pathologies such as cancer or inflammatory ...
Claudia Giménez-Campillo   +7 more
doaj   +1 more source

Pteridines and Lipid Metabolism

open access: yesPteridines, 1998
The effect of 9 different pteridines on fatty acid incorporation into phospholipids as well as on cholesterol and phospholipid content was compared in vitro using rat liver homogenate, Krebs-Ringer phosphate buffer containing 0.3 % albumin (pH=7.4 ...
Rudzite Vera   +5 more
doaj   +1 more source

Oil Things Bright and Beautiful? How Hydrocarbon Pollution Impacts Guppy Ornamentation. [PDF]

open access: yesEcol Evol
Spatial variation in crude oil pollution in Trinidad leads to differing levels of pollutant exposure in connected guppy populations. Male guppy ornamentation is an important sexually selected trait affected by environmental changes. Measuring area and intensity of this ornamentation, we found guppies from anthropogenically polluted habitats had greater
McGovern HR   +3 more
europepmc   +2 more sources

Solvent Effects upon the Electronic Absorption and Fluorescence Spectra of Pteridines and Riboflavin and Their Ground and First Excited Singlet State Dipole Moments

open access: yesPteridines, 1991
The electronic absorption. fluorescence excitation, and fluorescence emission spectra of a series of pteridines (lumazine, xanthopterin, isoxanthopterin, biopterin) and riboflavin (vitamin B2) were measured at room temperature (298 K) in a number of ...
Aaron J.-J.   +8 more
doaj   +1 more source

Pteridines, XCVI. Synthesis and Reactions of 6-(1,2,3-Trihydroxypropyl)pteridines

open access: yesPteridines, 1990
Various hydropyrano [3.2-g] pteridines (7, 10, 12, 21 , 33) were oxidized to the corresponding 6-(1,2,3- trihydroxypropyl)pteridine derivatives (8,9, 11, 13,32, 34), which are valuable intermediates for the synthesis of new 6-substituted pteridines (15 -
Soyka Rainer, Pfleiderer Wolfgang
doaj   +1 more source

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