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Bicyclic 6-6 Systems: Pteridines [PDF]
, 2022 This article describes the literature on pteridines, covering the period from 2008 to 2020. The physical properties and reactions include photochemistry, substitution at ring nitrogens, nucleophilic substitution at ring carbons, organometallic couplings ...
Mehrnoosh Ostovar +3 more
core +1 more source
In silico and in vivo screening of triamterene synthetic analogues as promising diuretics
Medičnì Perspektivi, 2022 The modification of lead-compound aimed to the increasing of activity, decrement of toxicity or improvement of selectivity is one of the most important methods used for elaboration of novel medications.
K.V. Sokolova +4 more
doaj +1 more source
The Genetic Basis of Color Polymorphism in the Orb‐Web Spider Gasteracantha cancriformis [PDF]
Ecol EvolThis study investigates the genetic basis of coloration in the polymorphic spider Gasteracantha cancriformis using RNA‐seq data from different female color morphs. We assembled a reference transcriptome and identified differentially expressed genes associated with known pigmentation pathways, including carotenoids, melanin, ommochromes, and pteridines.
Torres‐Quintero P +3 more
europepmc +2 more sources
Pteridines, 2017 Conjugated and unconjugated pteridines and their derivatives are important cofactors in cellular metabolism. Hence, the amount of unconjugated pteridines in biological fluids has been found to be modified as a result of several disorders. It is necessary
Espinosa-Mansilla Anunciación +1 more
doaj +1 more source
Pteridines in the Assessment of Neoplasia [PDF]
cclm, 1982 Biological processes which might explain the association of pteridine excretion with proliferation are still unknown. Difficulties in the analysis and the determination of naturally occurring pteridines are described. The best quantitative estimations were achieved when measurement of non-reduced forms was attempted.
HAUSEN, A., Wachter, H.
openaire +2 more sources
Allergology International, 2019 Background: Pteridines are metabolites of tetrahydrobiopterin, which serves as co-enzyme of nitric oxide synthase. We sought to investigate the usefulness of pteridines as biomarkers for childhood asthma control.
Saki Kasuga +10 more
doaj +1 more source
Pharmaceuticals, 2023 Structural-based drug design and solvent-free synthesis were combined to obtain three novel series of 5-arylethylidene-aminopyrimidine-2,4-diones (4, 5a–c, 6a,b), 5-arylethylidene-amino-2-thiopyrimidine-4-ones (7,8), and 6-arylpteridines (9,10) as dual ...
Samar El-Kalyoubi +4 more
doaj +1 more source
Pteridines, 1995 Unconjugated pteridines are present in fungi, algae and plants. However, the functions of pteridines in these organisms are not thoroughly investigated. The biosynthesis follows the same steps as were shown for animals and eubacteria.
Maier Josef +2 more
doaj +1 more source
Influence of Neopterin on Ciliary Beat Frequency of Human Nasal Epithelial Cells in vitro
Pteridines, 2008 Acute infectious diseases of the respiratory tract are regularly associated with increased concentrations of neopterin in serum and/or urine. Most likely, the pteridine compound is not only a marker of an activated cellular immune system but may exert ...
Neher Andreas +5 more
doaj +1 more source
Chemosensors, 2023 Pteridines are a group of compounds synthesised by many living organisms that are involved in the metabolism of many cofactors and vitamins. Their concentration in biological fluids may be altered by various pathologies such as cancer or inflammatory ...
Claudia Giménez-Campillo +7 more
doaj +1 more source