Tetrahydro-6-biopterin is associated with tetrahydro-7-biopterin in primary murine mast cells [PDF]
FEBS Letters, 1992 Murine bone marrow‐derived mast cells proliferate in response to interleukin 3. In addition to 6‐biopterin, 7‐biopterin was identified in these cells by HPLC analysis of iodine oxidized extracts and by alkaline permanganate oxidation to the 6‐ and 7‐carboxylic acids. 7‐Biopterin comprised 31.9 (± 7.7)% of the total biopterin.
Ziegler, Irmgard, Hültner, Lothar
exaly +3 more sources
An Efficient Synthesis of 2'-O-(β-D-Ribofuranosyl)biopterin
Pteridines, 2008 N2-(N,N-Dimethylaminomethylene)-3-[2-(4-nitrophenyl)ethyl]-1',2'-di-O-(trimethylsilyl)biopterin (4) was prepared from biopterin (1a, 86% overall yield) in 5 steps.
Hanaya Tadashi +5 more
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A systematic review and meta-analysis of pteridines in mild cognitive impairment and Alzheimer’s disease [PDF]
BMC GeriatricsBackground Alterations in specific pteridine metabolites, particularly neopterin, biopterin, and tetrahydrobiopterin have been reported in mild cognitive impairment, Alzheimer’s disease, and other types of dementia.
Arduino A. Mangoni, Angelo Zinellu
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Pteridines, 1995 The levels of neopterin, biopterin and the neopterin/biopterin ratio (NIB) were measured in urine samples taken from normal young and elderly control subjects, exceptionally healthy elderly control subjects classified according to the 'Senieur' protocol ...
Armstrong R.A. +3 more
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Comparative metabolism of conjugated and unconjugated pterins in Crithidia, Leishmania and African trypanosomes. [PDF]
PLoS Neglected Tropical DiseasesMammalian cells synthesise tetrahydrobiopterin de novo, an essential cofactor for hydroxylation of aromatic amino acids, cleavage of ether lipids and the synthesis of nitric oxide.
Han B Ong, Susan Wyllie, Alan H Fairlamb
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The kynurenine and serotonin pathway, neopterin and biopterin in depressed children and adolescents: an impact of omega-3 fatty acids, and association with markers related to depressive disorder. A randomized, blinded, prospective study [PDF]
Frontiers in PsychiatryDepressive disorder is a severe mental condition. In addition to genetic factors, immunological-inflammatory factors, oxidative stress, and disturbances in neurotransmitter metabolism, kynurenine and serotonin pathways may play a role.
Lucia Ilavská +7 more
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Dystonia and Biopterin Deficiency
Pediatric Neurology Briefs, 1988 Five patients with childhood dystonia associated with reduced CSF biopterin, responsive to levodopa, and characterized by diurnal and exertional variation are reported from the Developmental and Metabolic Neurology Branch, National Institute of ...
J Gordon Millichap
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Evaluation of neopterin levels and kynurenine pathway in patients with acute coronary syndrome [PDF]
Acute and Critical Care, 2023 Background Coronary atherosclerosis is the leading cause of coronary artery disease. Several investigations have indicated that tear-sensitive plaques contain macrophages and T cells. Neopterin is an essential cellular immune response biomarker. The main
Ibrahim Kember +4 more
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The High Concentration of Biopterin In Breast Milk and It's Absorption During the Neonatal Period
Pteridines, 1995 Breast milk has been found to contain high levels of biopterin compounds, whose physiological roles have attracted attention through newly discovered functions, particularly. as a cofactor for biosynthesis of nitric oxide.
Iizuka Tadashi +7 more
doaj +1 more source
Pteridines, 1990 Enzymatic conversion of stereoisomers of biopterin (3a-d) to the 7-oxo-biopterin isomers (4a-d) was performed with a new pterin 7-oxidase extracted from carp skin.
Takikawa Shin Ichiro, Matsuura Sadao
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