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Neopterin, Inflammation, and Oxidative Stress: What Could We Be Missing?
Neopterin has been extensively used as a clinical marker of immune activation during inflammation in a wide range of conditions and stresses. However, the analysis of neopterin alone neglects the cellular reactions that generate it in response to ...
Steven Gieseg, Angus Lindsay
exaly +3 more sources
Urinary Neopterin in Malignant Lymphoma
Urinary neopterin levels were studied in 96 patients with malignant lymphomas. Twenty-eight had Hodgkin's disease and 68 non-Hodgkin's lymphoma. Neopterin excretion was significantly related to the clinical stage of the disease.
L. Piccinini +4 more
doaj +4 more sources
Neopterin measurement in clinical diagnosis [PDF]
Neopterin is a marker associated with cell-mediated immunity. It is produced in monocytes/macrophages primarily upon stimulation with interferon-gamma. Due to its chemical structure, neopterin belongs to the class of pteridines. It is excreted in an unchanged form via the kidneys. Serum levels above 10 nmol/L are regarded as elevated.
A, Berdowska, K, Zwirska-Korczala
exaly +3 more sources
Knee and hip arthroplasty are common surgeries within an aging population. Some data has suggested that knee arthroplasty is more traumatic to the body than hip arthroplasty due to the increased complexity and load bearing nature of the joint.
Gregory Baxter-Parker +6 more
doaj +1 more source
Cerebrospinal fluid neopterin analysis in neuropediatric patients: establishment of a new cut off-value for the identification of inflammatory-immune mediated processes. [PDF]
ObjectiveA high level of cerebrospinal fluid (CSF) neopterin is a marker of central nervous system inflammatory-immune mediated processes. We aimed to assess data from 606 neuropediatric patients, describing the clinical and biochemical features of those
Marta Molero-Luis +7 more
doaj +1 more source
Neopterin as an endogenous antioxidant [PDF]
The in vitro potency of neopterin (NP) as an antioxidant and its in vivo activity to suppress alloxan‐induced diabetes were investigated. The reduced form of neopterin, 5,6,7,8‐tetrahydroneopterin (NPH‐4), showed an extremely high superoxide anion radical scavenging activity in two assay systems, i.e.
Kojima, Shuji +3 more
openaire +2 more sources
Urinary neopterin concentrations vs total neopterins for clinical utility. [PDF]
Abstract Neopterin measurements are especially useful as an early marker in (e.g.) allograft rejections and in patients infected with human immunodeficiency virus type 1 (HIV-1). An increased concentration of total neopterins (neopterin + dihydroneopterin) is also a significant marker in patients with HIV-1 infection.
Fuchs, Dietmar +7 more
openaire +3 more sources
Objective: The aim of this study was to examine the activity of immune system in patients with major depression by using serum neopterin levels as a biochemical tool.
Cemil Çelik +5 more
doaj
Serum Neopterin in Patients with Malignant Melanoma
Increased serum or urinary concentrations of neopterin have been described in patients with tumors of different primary locations, but reports on neopterin in patients with melanoma are scanty. We have studied serum neopterin and a melanoma marker, S-100-
Beneš Petr +7 more
doaj +1 more source
Urinary Neopterin in Patients with upper Gastrointestinal, Biliary and Pancreatic Carcinomas
Increased urinary neopterin has been associated with advanced disease and poor prognosis in patients with colorectal carcinoma, but less is known about urinary neopterin in other gastrointestinal tumors.
Melichar Bohuslav +4 more
doaj +1 more source

