Results 1 to 10 of about 902 (137)

Age-Dependent Variation in Blood Biopterin Peaks Following Oral Tetrahydrobiopterin Administration in Phenylketonuria. [PDF]

J Inherit Metab Dis
ABSTRACT The correct diagnosis of tetrahydrobiopterin (BH4, sapropterin dihydrochloride)‐responsive phenylketonuria (PKU) and treatment with BH4 are important for prognosis and quality of life. We examined whether age affects biopterin bioavailability following oral BH4 administration in PKU and whether this influences BH4 responsiveness.
Kitayama K, Sakaguchi T, Nakano N, Kabata D, Shintaku H, Hamazaki T.   +5 more
europepmc   +2 more sources

Inducible Endothelial <i>Gch1</i> Deletion Reveals Rapid, Sex-Specific Effects on Blood Pressure and Pregnancy Outcomes. [PDF]

Hypertension
Chuaiphichai S, Au-Yeung D, Whiteman CAR, Cook SL, McNeill E, Douglas G, Channon KM.   +6 more
europepmc   +1 more source

Exploring the Mystery of the Tetrahydrobiopterin Synthetic Defect Lethal Mutant lem^l from Birth to Death in the Silkworm Bombyx mori. [PDF]

Int J Mol Sci, 2022
Liang D, Shu R, Jiang S, Xu M, Cai Y, Qin H, Zhang D, Feng M, Gao J, Meng Y.   +9 more
europepmc   +1 more source

Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling. [PDF]

Nat Commun
Fontana J, Sparkman-Yager D, Faulkner I, Cardiff R, Kiattisewee C, Walls A, Primo TG, Kinnunen PC, Garcia Martin H, Zalatan JG, Carothers JM.   +10 more
europepmc   +1 more source

Methotrexate-Induced Leukoencephalopathy as a Clinical and Radiological Mimicker of Acute Ischemic Stroke Leading to Thrombolysis. [PDF]

Cureus
Panicker VV, Radhakrishnan SE, Kuruttukulam GV, Bose JA, Favas TT.   +4 more
europepmc   +1 more source

Biopterin

VITAMINS, 1956
openaire   +1 more source

Syntheses of optically active monapterin, 7,8-dihydromonapterin, and 5,6,7,8-tetrahydromonapterin from l-xylose. [PDF]

RSC Adv
Ghosh AK, Sharma A, Nagam S, Fuqua C.
europepmc   +1 more source

No QTcF Prolongation with Sepiapterin: Results From a Thorough QT Study in Healthy Subjects at Therapeutic and Supratherapeutic Doses. [PDF]

J Clin Pharmacol
Gao L, Xue H, Darpo B, Ingalls K, Kaushik D, Smith N, Kong R, Golden L.   +7 more
europepmc   +1 more source

Evaluation of the Antileishmanial Activity of Some Benzimidazole Derivatives Using In Vitro and In Silico Techniques. [PDF]

Vet Sci
Eser M, Çavuş İ, Kaya AZ, Evren AE, Yurttaş L.   +4 more
europepmc   +1 more source

Mechanism of auranofin toxicity: Inhibition of tetrahydrobiopterin metabolism. [PDF]

Toxicol Appl Pharmacol
Yang S, Jan YH, Richardson JR, Heck DE, Laskin JD.   +4 more
europepmc   +1 more source