Results 41 to 50 of about 9,485 (209)

Association Between Neopterin Production and other Parameters in a Population of Blood Donors

open access: yesPteridines, 2002
Neopterin is released from human monocyte-derived macrophages preferentially upon stimulation with the Thlcell cytokine interferon-γ. In humans, increased concentrations of neopterin in serum and urine have been found in viral infections including human ...
Schennach Harald   +5 more
doaj   +1 more source

Nailfold capillary phenotypes distinguish juvenile myositis subtypes and associate with disease activity

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Nailfold capillaroscopy is a non‐invasive imaging tool that can aid in the diagnosis and monitoring of juvenile myositis. Branched nailfold capillary morphology is more common in juvenile myositis patients, particularly those positive for TIF1γ+ autoantibodies. Juvenile myositis patients with more active disease demonstrate increased microhaemorrhages,
Nicholas McClellan   +7 more
wiley   +1 more source

Systemic Immune Activation, Anemia and Thrombocytosis in Breast Cancer Patients Treated by Doxorubicin and Paclitaxel

open access: yesPteridines, 2006
Increased urinary concentrations of neopterin, an indicator of systemic immune activation, have been reported only in a minority of patients with breast cancer. We determined urinary neopterin by high-performance liquid chromatography in 78 patients with
Melichar Bohuslav   +5 more
doaj   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1702-1710, August 2026.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez   +10 more
wiley   +1 more source

Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific [PDF]

open access: yes, 1992
Krämer A, Biggar RJ, Hampl H, et al. Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific. American Journal of Epidemiology.
Biggar, Robert J.   +6 more
core  

Comparison between plasma neopterin and the urine neopterin : creatinine ratio as inflammatory biomarkers [PDF]

open access: yes, 2019
: Background: Neopterin, a product of cell-mediated immunity, is a non-specific biomarker of inflammation. Plasma/serum is generally the body fluid of choice for neopterin assessment, but urine is often used as it does away with venepuncture. Analysis of
Thomas, Bianca   +2 more
core   +1 more source

Effect of Neopterin on the Hematopoietic System

open access: yesPteridines, 2009
Neopterin is produced by monocytes and is a useful biomarker for inflammation. We recently found that neopterin is biologically active against hematopoiesis during inflammatory processes.
Tsuboi Isao, Aizawa Shin
doaj   +1 more source

Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions – A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aim Human T‐Lymphotropic virus type 1 (HTLV‐1) infection can lead to HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a debilitating chronic neurological disease characterized by progressive lower limb spasticity and autonomic dysfunction.
Meygol Mirzaei Rezaei   +11 more
wiley   +1 more source

Urinary Neopterin in Patients with Diabetes Mellitus and Foot Ulcers

open access: yesPteridines, 2007
Increased urinary or serum concentrations of neopterin have been reported in disorders associated with systemic immune activation, e.g. viral infections, cancer, or autoimmune diseases, but the data on neopterin concentrations in patients with diabetes ...
Melicharova Karolina   +5 more
doaj   +1 more source

Neopterin--its clinical use in urinalysis

open access: yes, 1994
Increased amounts of neopterin are released during cellular immune response. Neopterin concentrations can be monitored in serum and urine of patients since neopterin is removed from the circulation by renal excretion.
Stahl-Hennig, C.   +5 more
core   +2 more sources

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