Results 41 to 50 of about 13,713 (220)

Evaluating predictive markers for viral rebound and safety assessment in blood and lumbar fluid during HIV-1 treatment interruption [PDF]

, 2020
Background: Validated biomarkers to evaluate HIV-1 cure strategies are currently lacking, therefore requiring analytical treatment interruption (ATI) in study participants.
De Langhe, Nele, De Scheerder, Marie-Angélique, Fuchs, Dietmar, Gisslén, Magnus, Lemey, Philippe, Noppe, Ytse, Palmer, Sarah, Pelgrom, Jolanda, Rutsaert, Sofie, Trypsteen, Wim, Van Der Gucht, Beatrijs, Van Hecke, Clarissa, Van Wanzeele, Filip, Vandekerckhove, Linos, Vrancken, Bram, Zetterberg, Henrik   +15 more
core   +1 more source

Neopterin as an endogenous antioxidant [PDF]

FEBS Letters, 1992
The in vitro potency of neopterin (NP) as an antioxidant and its in vivo activity to suppress alloxan‐induced diabetes were investigated. The reduced form of neopterin, 5,6,7,8‐tetrahydroneopterin (NPH‐4), showed an extremely high superoxide anion radical scavenging activity in two assay systems, i.e.
Kojima, Shuji, Icho, Takeshi, Kajiwara, Yoshio, Kubota, Kazuhiko   +3 more
openaire   +2 more sources

Neopterin levels are independently associated with cardiac remodeling in patients with chronic heart failure [PDF]

, 2013
Neopterin, a marker of inflammation and monocyte activation, is found increased in patients with heart failure (HF). This study investigates whether neopterin levels correlate with left ventricular (LV) remodeling and brain natriuretic peptide (BNP), a ...
Belli, Oriana, Campolo, Jonica, Caruso, Raffaele, Cozzi, Lorena, De Chiara, Benedetta, Frigerio, Maria, Moreo, Antonella, Musca, Francesco, Parodi, Oberdan, Parolini, Marina, Verde, Alessandro   +10 more
core   +1 more source

Aicardi‐Goutières Syndrome Type 6: Case Report and Structural Prediction Supporting a Dominant‐Negative Effect of the ADAR1 c.3019G>A Variant

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Aicardi–Goutières syndrome type 6 (AGS6) is a genetically determined autoinflammatory disorder, classically inherited in an autosomal recessive manner. We report a Czech child with a heterozygous ADAR1 NM_001111.5:c.3019G>A variant causing AGS6.
Katerina Turan, Petra Pokorna, Kamila Rihova, Jana Kubatova, Katerina Kozelkova, Eliska Hlouskova, Pavlina Danhofer, Petr Jabandziev, Jiri Damborsky, Regina Demlova, Ondrej Slaby, Katerina Slaba   +11 more
wiley   +1 more source

Effect of Neopterin on the Hematopoietic System

Pteridines, 2009
Neopterin is produced by monocytes and is a useful biomarker for inflammation. We recently found that neopterin is biologically active against hematopoiesis during inflammatory processes.
Tsuboi Isao, Aizawa Shin
doaj   +1 more source

Scoping studies to establish the capability and utility of a real-time bioaerosol sensor to characterise emissions from environmental sources [PDF]

, 2018
A novel dual excitation wavelength based bioaerosol sensor with multiple fluorescence bands called Spectral Intensity Bioaerosol Sensor (SIBS) has been assessed across five contrasting outdoor environments.
Alexis Attwood, Allan Bennett, Anderson, Bauer, Ben Williams, Borlée, Bünger, Catherine Rolph, Crawford, Crawford, Douglas, Enda Hayes, Frederic Coulon, Gabey, Gabey, Gabey, Gill Drew, Hallar, Hernandez, Hill, Huffman, Huffman, Huffman, Jahne, Kaye, Kerry Walsh, Li, Madsen, Mazar, Morris, O'Connor, O'Connor, O'Connor, Pan, Pan, Pankhurst, Pearce, Pearson, Perring, Pöhlker, Robert P. Kinnersley, Robinson, Roshchina, Saari, Samuel Collins, Schumacher, Sean Tyrrel, Shagun Khera, Sialve, Simon J.T. Pollard, Simon Jackson, Simon Parks, Sonia Garcia Alcega, Sun, Sykes, Taha, Taha, Taha, Toni Gladding, Toprak, van der Hoek, Vestlund, Walser, Wei, Yu, Zaheer Ahmad Nasir, Ziemba   +66 more
core   +6 more sources

Neopterin as Tumour Marker Serum and Urinary Neopterin Concentrations in Malignant Diseases [PDF]

Clinical Chemistry and Laboratory Medicine, 1986
Serum and urinary neopterin concentrations were measured in 142 patients suffering from various malignant diseases. Increased serum and urinary neopterin levels were found in 48% and 55% of patients respectively. Neopterin showed sufficient sensitivity in the detection of haematological disorders and hypernephroma, whereas the sensitivity of neopterin ...
Kuzmits, R., Ludwig, H., Legenstein, Elisabeth, Szekeresz, T., Kratzik, C., Hofbauer, J.   +5 more
openaire   +3 more sources

Nutrigenomic Potentials of Phytobiotics Against Heat Stress and Allied Afflictions in Livestock Species–An In Silico Supported Review

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Heat stress impairs livestock performance through oxidative stress, immune dysregulation, and reduced productivity. Phytobiotics act as natural mitigators with antioxidant, anti‐inflammatory, antimicrobial, and gut‐modulatory effects. Mechanistically, they regulate HSPs, Nrf2, NF‐κB, and MAPK pathways.
Xiaoyan Wang, Ting Yuan, Muhammad Asif Arain, Mohammed Al‐Rasheed, Aftab Shaukat   +4 more
wiley   +1 more source

Urinary Neopterin in Patients with Diabetes Mellitus and Foot Ulcers

Pteridines, 2007
Increased urinary or serum concentrations of neopterin have been reported in disorders associated with systemic immune activation, e.g. viral infections, cancer, or autoimmune diseases, but the data on neopterin concentrations in patients with diabetes ...
Melicharova Karolina, Kusalova Marie, Smahelova Alena, Hyspler Radomir, Solichova Dagmar, Melichar Bohuslav   +5 more
doaj   +1 more source

The Effects of Neopterin on the Viability and Motility of Different HCC Cell Lines

Proceedings, 2018
Increased neopterin levels reflect the activation of the cellular immune system which is of importance in the pathogenesis and progression of various diseases such as cancer.
Imge Kunter, Marianna Najjar, Yelin Subasi, Niloofar Zabib, Gonul Sahin   +4 more
doaj   +1 more source