Results 41 to 50 of about 5,734 (184)

Neopterin as an Endogenous Antioxidant.

Eisei kagaku, 1995
Summary The in vitro antioxidative activity of neopterin and its in vivo potency to suppress gastric ischemia were investigated. The scavenging activity of the reduced form of neopterin, 5,6,7,8-tetrahydroneopterin (NPH4), against ...
openaire   +3 more sources

Longitudinal changes in plasma biomarkers of immune activation, neuronal inflammation and injury in persons with HIV initiating ART

HIV Medicine, Volume 27, Issue 7, Page 1132-1143, July 2026.
Abstract Background Data on changes in biomarkers of brain health, and their associations with cognitive function in adults commencing either dual‐ or triple‐antiretroviral therapy (ART) are sparse. Methods Plasma biomarkers (neurofilament light [NfL], glial fibrillary acidic protein [GFAP], sCD14, CXCL10, neopterin and IL‐6) were measured at baseline ...
Merle Henderson, Peter Dutey‐Magni, Carolina Herrera, Wolfgang Stöhr, Alejandro Arenas‐Pinto, Owen Swann, Amanda Heslegrave, Henrik Zetterberg, John Tregoning, Sarah Fidler, François Raffi, Andrea Calcagno, Ab Babiker, Alan Winston   +13 more
wiley   +1 more source

Evaluation of Red Blood Cell Biomechanics in the Setting of Cancer‐Associated Anemia and Chemotherapy

Microcirculation, Volume 33, Issue 5, July 2026.
ABSTRACT Introduction Red blood cells (RBCs) possess distinct biomechanical properties that enable their survival and efficient oxygen delivery. Cancer‐associated anemia, frequently compounded by chemotherapy, is a major clinical challenge, yet little is known about how RBC biomechanics contribute to its pathophysiology.
Deirdre Finnigan, Nick Cruickshanks, George Ilbawi, Regan Bucciol, Yousra Tera, Maha Othman   +5 more
wiley   +1 more source

Influence of Three Different Diet Modes Combined with Exercise Loads on Urinary and Plasma Neopterin Concentrations: A Longitudinal Study

Pteridines, 1997
During six months, we studied the influence of three extremely different diet modes (normal diet, carbohydrate- rich diet, fat-rich diet) combined with three defined exercise loads (step test, endurance test fo r 30 minutes, endurance test for 90 minutes)
Lamprecht Manfred, Mlekusch Walter, Vrecko Karoline, Reibnegger Gilbert   +3 more
doaj   +1 more source

Neopterin Counters Vascular Inflammation and Atherosclerosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundNeopterin, a metabolite of GTP, is produced by activated macrophages and is abundantly expressed within atherosclerotic lesions in human aorta and carotid and coronary arteries.
Remina Shirai, Kengo Sato, Tomoyuki Yamashita, Maho Yamaguchi, Taisuke Okano, Kaho Watanabe‐Kominato, Rena Watanabe, Taka‐aki Matsuyama, Hatsue Ishibashi‐Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu Hirano, Takuya Watanabe   +12 more
doaj   +1 more source

Acute Disseminated Encephalomyelitis Presenting as Fever of Unknown Origin in a 4‐Year‐Old Boy: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT A 4‐year‐old boy presented with prolonged fever of unknown origin and systemic inflammation without early neurological signs. MRI revealed multifocal demyelination, and MOG antibodies were positive. He was diagnosed with ADEM and treated with steroids and IVIg, but relapsed twice, consistent with multiphasic disseminated encephalomyelitis ...
Pedro Pau
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Effects of extreme mountain ultramarathon on stress‐related biomarkers from multiple biological matrices in adult male runners

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Prior investigations concerning finishers of the Tor des Géants (TDG) have demonstrated oxi‐inflammatory response. MicroRNAs (miRNAs) have been identified as prospective biomarkers for oxi‐inflammatory and stress responses. This study addressed the acute responses concerning salivary miRNAs, circulating redox markers and urinary exercise ...
Cristina Purcaro, Ester Sara Di Filippo, Alessandra Vezzoli, Danilo Bondi, Guido Giardini, Stefania Fulle, Vittore Verratti, Simona Mrakic‐Sposta   +7 more
wiley   +1 more source

The relationship between neopterin and hepatitis B surface antigen positivity

Pteridines, 2018
Hepatitis B is a life-threatening viral liver infection caused by the hepatitis B virus. Neopterin is regarded as an immunologic biomarker of several diseases related to activation of the cellular immune system.
Ünüvar Songül Ü, Aslanhan Hamza, Tanrıverdi Zübeyde, Karakuş Fuat   +3 more
doaj   +1 more source

Cytokine induction of neopterin production

Clinical and Experimental Immunology, 1991
SUMMARYThe pteridine neopterin is a marker of immunological activation and has been shown to be a useful marker of graft-versus-host disease (GVHD) in bone marrow transplant patients. High levels of both neopterin and interferon-gamma (IFN-γ) were produced in vitro during mixed lymphocyte responses, which may be considered to be a model of the primary ...
D C, Henderson, J, Sheldon, P, Riches, J R, Hobbs   +3 more
openaire   +3 more sources