Results 41 to 50 of about 5,716 (181)

“Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches—A Narrative Review”

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Reaction in leprosy is an immune‐mediated acute inflammatory episodes that occur in the natural course of Hansen's disease. Reaction can occur before, during, or after starting multidrug therapy and is a major cause of nerve damage, morbidity, and disability in affected individuals.
Bhaskar Gupta, Manesha Singh, Mohamad Goldust, Kinnor Das, Surajit Gorai, Prajwal Pudasaini, Seema Sitaula, Achyut Pokhrel, Esna Thapa, Sunil Jaiswal   +9 more
wiley   +1 more source

Neopterin as an Endogenous Antioxidant.

Eisei kagaku, 1995
Summary The in vitro antioxidative activity of neopterin and its in vivo potency to suppress gastric ischemia were investigated. The scavenging activity of the reduced form of neopterin, 5,6,7,8-tetrahydroneopterin (NPH4), against ...
openaire   +3 more sources

Is Environmental Enteric Dysfunction Reversible in Adults? A 7‐Year Observational Follow‐up Study of Histological and Biomarker Outcomes in Urban Bangladesh

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Environmental Enteric Dysfunction (EED) is a subclinical condition of the small intestine linked to chronic inflammation, impaired absorption, which results in undernutrition. While extensively studied in children, its persistence and reversibility in adults remain poorly characterised.
A. H. M. Rezwan, Ar‐Rafi Khan, Shaumik Islam, Md Fuad Al Fidah, Mehjabin Tishan Mahfuz, S. M. Tafsir Hasan, Md. Shabab Hossain, Mustafa Mahfuz, Tahmeed Ahmed   +8 more
wiley   +1 more source

Influence of Three Different Diet Modes Combined with Exercise Loads on Urinary and Plasma Neopterin Concentrations: A Longitudinal Study

Pteridines, 1997
During six months, we studied the influence of three extremely different diet modes (normal diet, carbohydrate- rich diet, fat-rich diet) combined with three defined exercise loads (step test, endurance test fo r 30 minutes, endurance test for 90 minutes)
Lamprecht Manfred, Mlekusch Walter, Vrecko Karoline, Reibnegger Gilbert   +3 more
doaj   +1 more source

Neopterin Counters Vascular Inflammation and Atherosclerosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundNeopterin, a metabolite of GTP, is produced by activated macrophages and is abundantly expressed within atherosclerotic lesions in human aorta and carotid and coronary arteries.
Remina Shirai, Kengo Sato, Tomoyuki Yamashita, Maho Yamaguchi, Taisuke Okano, Kaho Watanabe‐Kominato, Rena Watanabe, Taka‐aki Matsuyama, Hatsue Ishibashi‐Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu Hirano, Takuya Watanabe   +12 more
doaj   +1 more source

Aicardi‐Goutières Syndrome Type 6: Case Report and Structural Prediction Supporting a Dominant‐Negative Effect of the ADAR1 c.3019G>A Variant

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Aicardi–Goutières syndrome type 6 (AGS6) is a genetically determined autoinflammatory disorder, classically inherited in an autosomal recessive manner. We report a Czech child with a heterozygous ADAR1 NM_001111.5:c.3019G>A variant causing AGS6.
Katerina Turan, Petra Pokorna, Kamila Rihova, Jana Kubatova, Katerina Kozelkova, Eliska Hlouskova, Pavlina Danhofer, Petr Jabandziev, Jiri Damborsky, Regina Demlova, Ondrej Slaby, Katerina Slaba   +11 more
wiley   +1 more source

Nutrigenomic Potentials of Phytobiotics Against Heat Stress and Allied Afflictions in Livestock Species–An In Silico Supported Review

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Heat stress impairs livestock performance through oxidative stress, immune dysregulation, and reduced productivity. Phytobiotics act as natural mitigators with antioxidant, anti‐inflammatory, antimicrobial, and gut‐modulatory effects. Mechanistically, they regulate HSPs, Nrf2, NF‐κB, and MAPK pathways.
Xiaoyan Wang, Ting Yuan, Muhammad Asif Arain, Mohammed Al‐Rasheed, Aftab Shaukat   +4 more
wiley   +1 more source

Return to an extreme environment exposure after pulmonary infection: SCUBA diving as a model? [PDF]

Physiol Rep
Graphical overview of the experimental protocol used to investigate post‐COVID physiological responses during scuba diving at three different depths. Abstract The human body implements several adaptive mechanisms to perform in extreme environments. Increasingly, individuals return to such conditions after pulmonary infections, raising concerns about ...
Cialoni D, Brizzolari A, Mrakic‐Sposta S, Vezzoli A, Dellanoce C, Pieri M, Pelliccia R, Petrassi C, Bosco G, Barassi A, Marroni A.   +10 more
europepmc   +2 more sources

The relationship between neopterin and hepatitis B surface antigen positivity

Pteridines, 2018
Hepatitis B is a life-threatening viral liver infection caused by the hepatitis B virus. Neopterin is regarded as an immunologic biomarker of several diseases related to activation of the cellular immune system.
Ünüvar Songül Ü, Aslanhan Hamza, Tanrıverdi Zübeyde, Karakuş Fuat   +3 more
doaj   +1 more source

Cytokine induction of neopterin production

Clinical and Experimental Immunology, 1991
SUMMARYThe pteridine neopterin is a marker of immunological activation and has been shown to be a useful marker of graft-versus-host disease (GVHD) in bone marrow transplant patients. High levels of both neopterin and interferon-gamma (IFN-γ) were produced in vitro during mixed lymphocyte responses, which may be considered to be a model of the primary ...
D C, Henderson, J, Sheldon, P, Riches, J R, Hobbs   +3 more
openaire   +3 more sources