Results 61 to 70 of about 9,485 (209)
ABSTRACT HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy (ART) suppresses viral replication, it does not eradicate the virus, and metabolic dysregulation persists despite treatment.
Levanco K. Asia +4 more
wiley +1 more source
Prevalence and Correlates of Environmental Enteric Dysfunction Among Young Children in Bangladesh
ABSTRACT Bangladesh continues to experience high levels of child undernutrition, with stunting affecting approximately 24% of children under 5 years of age. Environmental enteric dysfunction (EED), a subclinical intestinal disorder characterized by chronic inflammation, immune activation, and nutrient malabsorption, may reduce the effectiveness of ...
Lauren Thompson +9 more
wiley +1 more source
The relationship between neopterin and hepatitis B surface antigen positivity
Hepatitis B is a life-threatening viral liver infection caused by the hepatitis B virus. Neopterin is regarded as an immunologic biomarker of several diseases related to activation of the cellular immune system.
Ünüvar Songül Ü +3 more
doaj +1 more source
ABSTRACT Introduction Red blood cells (RBCs) possess distinct biomechanical properties that enable their survival and efficient oxygen delivery. Cancer‐associated anemia, frequently compounded by chemotherapy, is a major clinical challenge, yet little is known about how RBC biomechanics contribute to its pathophysiology.
Deirdre Finnigan +5 more
wiley +1 more source
Urinary Neopterin Concentrations in Healthy Individuals with Household Contact
Increased neopterin concentrations in serum and urine indicate activation of cell-mediated immunity. In this study, urinary neopterin concentrations of a family consisting of 1 child (aged 5 years), her parents, and her grandparents were determined over ...
Winkler Christiana +3 more
doaj +1 more source
ABSTRACT A 4‐year‐old boy presented with prolonged fever of unknown origin and systemic inflammation without early neurological signs. MRI revealed multifocal demyelination, and MOG antibodies were positive. He was diagnosed with ADEM and treated with steroids and IVIg, but relapsed twice, consistent with multiphasic disseminated encephalomyelitis ...
Pedro Pau
wiley +1 more source
The role of Neopterin in cardiovascular disease
Inflammation plays a key role in the initiation and progression of atherosclerosis but also in the pathophysiology of atheromatous plaque disruption and the development of acute coronary syndromes. Neopterin is a marker of inflammation and of immune system activation, it is synthesized by macrophages, that, once activated, release this substance ...
Pacileo, M. +9 more
openaire +5 more sources
Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin +2 more
wiley +1 more source
Urinary Neopterin in Patients with Ovarian Cancer
Urinary neopterin, an indicator of systemic immune activation, is increased in most patients with epithelial ovarian carcinoma (EOC) and is an independent prognostic indicator.
Melichar Bohuslav +8 more
doaj +1 more source
Nutraceutical Interventions in Stunting: Advances, Challenges, and Prospects
Schematic representation of nutraceutical mechanisms in the management of stunting, illustrating an integrative pathway from pathological etiology to therapeutic outcome. (Left) Chronic malnutrition and recurrent infections contribute to gut dysbiosis and environmental enteric dysfunction (EED), leading to systemic inflammation and growth faltering ...
Souvia Rahimah +8 more
wiley +1 more source

