Results 61 to 70 of about 10,411 (162)

Neopterin and Its Clinical Significance In Autoimmune Diseases: a Minireview

open access: yesPteridines, 1993
Neopterin, a biochemical marker for the activation of cellular immune responses, is produced in large amounts specifically from macrophages upon stimulation with interferon-gamma (IFN-a).
Leohirun Lakana   +3 more
doaj   +1 more source

Determination of neopterin in urine of industrial workers by HPLC

open access: yesAnais da Academia Brasileira de Ciências, 2022
This study aimed to determine neopterin levels in the urine of industrial workers by the high-performance liquid chromatography method. Intra- and inter-day precision values for neopterin in urine were less than 3.14, and accuracy (relative error) was ...
BILAL YILMAZ   +3 more
doaj   +1 more source

Urinary Neopterin in Patients with Diabetes Mellitus and Foot Ulcers

open access: yesPteridines, 2007
Increased urinary or serum concentrations of neopterin have been reported in disorders associated with systemic immune activation, e.g. viral infections, cancer, or autoimmune diseases, but the data on neopterin concentrations in patients with diabetes ...
Melicharova Karolina   +5 more
doaj   +1 more source

Nationwide Epidemiology of Motor Neuron Diseases in Latvia (2020–2024): Incidence, Prevalence, and Clinical Characteristics

open access: yesEuropean Journal of Neurology, Volume 33, Issue 8, August 2026.
This first nationwide study of motor neuron diseases (MNDs) in Latvia provides epidemiological and clinical data about 181 patients identified with motor neuron diseases during a 5‐year observational period revealing lower incidence and prevalence rates compared to other European countries.
Vladimirs Krutovs   +9 more
wiley   +1 more source

Early brain‐penetrant immunotherapy reverses interferon signature and improves motor outcome in a case of ADAR1‐related Aicardi‐Goutières syndrome

open access: yesClinical &Translational Immunology, Volume 15, Issue 7, 2026.
Abstract Objectives Aicardi‐Goutières syndrome (AGS) is a genetic interferonopathy resulting from defects in nucleic acid metabolism and subsequent enhanced type I interferon signalling. We report how an expedited genomic diagnosis in conjunction with natural history data can enable a long‐term brain‐penetrant anti‐inflammatory regimen to optimise ...
Russell C Dale   +13 more
wiley   +1 more source

Helicobacter pylori infection and neopterin

open access: yesPteridines, 2001
In order to find out whether chronic immune stimulation is associated with Helicobacter pylori infection we studied 425 healthy individuals (aged 57.6 ± 9.22 years, s.d.) who were performing a health check up without having any specific health problems ...
Ledochowski Maximilian   +3 more
doaj   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva   +5 more
wiley   +1 more source

Using neopterin to monitor stress in hypoxic and normoxic repeated sprint training in rugby players [PDF]

open access: yes, 2019
Objectives: Neopterin has been used as a stress marker in team sport athletes, but its use in monitoring stress in hypoxic training requires further investigation.
Olsen, PD   +6 more
core   +1 more source

Clinical Value of Neopterin In Infectious Complications

open access: yesPteridines, 1999
Neopterin, a pteridine intermediate metabolite in the biopterine synthetic pathway, is synthesized and secreted by monocyte/macrophages upon stimulation, mainly by gamma-interferon by activated T cells.
Iwagaki Hiromi   +5 more
doaj   +1 more source

Dysregulated Metabolism in People Living With HIV in the Modern ART‐Era: A Systematic Review of Targeted Metabolomics Studies

open access: yesReviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy (ART) suppresses viral replication, it does not eradicate the virus, and metabolic dysregulation persists despite treatment.
Levanco K. Asia   +4 more
wiley   +1 more source

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